{"id":"W2082986841","doi":"10.1016/s0166-6851(03)00201-9","title":"Selection at a γ-aminobutyric acid receptor gene in Haemonchus contortus resistant to avermectins/milbemycins","year":2003,"lang":"en","type":"article","venue":"Molecular and Biochemical Parasitology","topic":"Helminth infection and control","field":"Veterinary","cited_by":65,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Haemonchus contortus; Anthelmintic; Avermectin; Receptor; Chloride channel; Allele; GABA receptor; Gene; Ivermectin; gamma-Aminobutyric acid; Nematode; GABAA receptor; Acetylcholine receptor; Genetics; Molecular biology; Biochemistry; Anatomy; Zoology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001726009,0.0004080855,0.0002582988,0.0005836202,0.0003668876,0.0002543106,0.000344854,0.0005779637,0.002465253],"category_scores_gemma":[0.0002897572,0.0002585154,0.0003653177,0.0002040846,0.0003919252,0.0001125193,0.0002172799,0.0006431889,0.0003587123],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002620888,"about_ca_system_score_gemma":0.0001811091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002023215,"about_ca_topic_score_gemma":0.003187107,"domain_scores_codex":[0.9998043,0.00005233014,0.00001647379,0.0000347215,0.00003390333,0.00005834732],"domain_scores_gemma":[0.999727,0.00007791555,0.00004824056,0.00002503231,0.00002719534,0.00009459673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003521987,0.00008883929,0.0007222187,0.000009832764,0.0000124491,0.000365141,0.00004770877,0.00005102185,0.9977238,0.00006746173,0.00002467874,0.0005346058],"study_design_scores_gemma":[0.0004618403,0.005944348,0.1831584,0.00005332452,0.0002424445,0.01061108,0.0008973798,0.005504624,0.7890398,0.0002743191,0.003731062,0.00008131925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991837,0.00003434503,0.000250506,0.00004011705,0.000009316111,0.00001868597,0.00007294124,0.00001166255,0.0003788056],"genre_scores_gemma":[0.9975207,0.00005245167,0.0003744455,0.00005703862,0.000007501122,0.00001710832,0.0002093829,0.00002092936,0.001740295],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002465253,"threshold_uncertainty_score":0.008247077,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01792533318914236,"score_gpt":0.3057807534466304,"score_spread":0.287855420257488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}