{"id":"W2083008217","doi":"10.1016/j.vaccine.2008.02.072","title":"EV02: A Phase I trial to compare the safety and immunogenicity of HIV DNA-C prime-NYVAC-C boost to NYVAC-C alone","year":2008,"lang":"en","type":"article","venue":"Vaccine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":102,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sanofi (Canada)","funders":"Centre Hospitalier Universitaire Vaudois; Imperial College London; National Institute for Health and Care Research","keywords":"ELISPOT; Immunogenicity; Medicine; Regimen; Adverse effect; Immunology; Internal medicine; Asymptomatic; Gastroenterology; Virology; Surgery; Pharmacology; Immune system; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000287377,0.0002048588,0.0004895529,0.0001167438,0.0003550858,0.000007834809,0.0002850778,0.00007176035,0.0007553369],"category_scores_gemma":[0.0001557885,0.0001329251,0.0001011212,0.0002542023,0.00005132895,0.00004271376,0.0002277077,0.0001980643,0.0009811505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005270651,"about_ca_system_score_gemma":0.00009754035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000403643,"about_ca_topic_score_gemma":0.0001925148,"domain_scores_codex":[0.9985288,0.0002236144,0.0004155302,0.0003180263,0.00007178102,0.0004422401],"domain_scores_gemma":[0.9989843,0.0002083356,0.00008079309,0.0005251192,0.0001008867,0.000100505],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.2419028,0.002787671,0.008170862,0.00002548093,0.001303523,0.00007636471,0.003160138,0.00001041659,0.6725064,0.0001179116,0.05785999,0.01207841],"study_design_scores_gemma":[0.2097139,0.005833009,0.06602222,0.00005703192,0.0001496671,0.0003224897,0.0002680889,0.000004667463,0.4313016,0.00001610486,0.2858992,0.0004120122],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922967,0.002399886,0.0001551382,0.002759115,0.0001545218,0.001407179,0.0004859553,0.0000378699,0.0003036623],"genre_scores_gemma":[0.9966751,0.000213076,0.00008849491,0.0001923899,0.00005455017,0.00006086678,0.0002354646,0.00001587036,0.002464142],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2412048,"threshold_uncertainty_score":0.9997967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02434066180072997,"score_gpt":0.2942020633388696,"score_spread":0.2698614015381396,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}