{"id":"W2083070346","doi":"10.4161/cc.5.5.2489","title":"p53 Transcriptional Activation Domain: A Molecular Chameleon?","year":2006,"lang":"en","type":"review","venue":"Cell Cycle","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Biology; DNA; DNA damage; Cell biology; Transcription factor; Suppressor; HMG-box; Replication protein A; Transcriptional regulation; DNA-binding protein; Transcription (linguistics); DNA repair; DNA replication; DNA-binding domain; Plasma protein binding; Oligonucleotide; Phosphorylation; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001228479,0.0004486587,0.001150319,0.0002570854,0.00006558754,0.00002364002,0.0001461444,0.0005418051,0.0002367923],"category_scores_gemma":[0.00001391697,0.0004254269,0.000837566,0.0003629008,0.0000617586,0.00004658771,0.00002622846,0.0006768884,0.0003080567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004334088,"about_ca_system_score_gemma":0.0005028896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000312635,"about_ca_topic_score_gemma":0.000002528143,"domain_scores_codex":[0.9979858,0.0000942003,0.0005260379,0.0005640712,0.0004650018,0.0003649233],"domain_scores_gemma":[0.9989552,0.00003411273,0.000236666,0.0005511118,0.00006512884,0.0001577023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006677523,0.0007870205,7.722421e-7,0.033817,0.0004814097,0.0006402017,0.0001486185,0.00005780287,0.01622213,0.00133087,0.006229979,0.9402174],"study_design_scores_gemma":[0.0008716209,0.00009332087,0.000003765017,0.004804457,0.0008134748,0.0001177091,0.000007223141,0.000009477655,0.001037722,0.0001660798,0.991712,0.0003632039],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001740665,0.9714742,0.003239843,0.00007411605,0.0002702769,0.001293477,0.00004558927,0.000127256,0.02330119],"genre_scores_gemma":[0.0003357971,0.9955348,0.0007378395,0.0001844757,0.0003754182,0.0002107094,0.001380445,0.0001709337,0.001069542],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.985482,"threshold_uncertainty_score":0.9998198,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01922653938100196,"score_gpt":0.2835072522028336,"score_spread":0.2642807128218316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}