{"id":"W2083073031","doi":"10.1111/bjh.12985","title":"Use of <scp>JAK</scp> inhibitors in the management of myelofibrosis: a revision of the <scp>B</scp>ritish <scp>C</scp>ommittee for <scp>S</scp>tandards in <scp>H</scp>aematology <scp>G</scp>uidelines for <scp>I</scp>nvestigation and <scp>M</scp>anagement of <scp>M</scp>yelofibrosis 2012","year":2014,"lang":"en","type":"letter","venue":"British Journal of Haematology","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"Medical Research Council; Public Health Agency","keywords":"Ruxolitinib; Myelofibrosis; Medicine; Hazard ratio; Internal medicine; Calreticulin; Confidence interval; Hematology; Oncology; Biology; Bone marrow; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005988462,0.0004821621,0.001207839,0.001422345,0.001106239,0.00183212,0.001603018,0.002853409,0.001526046],"category_scores_gemma":[0.008569784,0.0003405718,0.001693612,0.001135989,0.001495929,0.001530639,0.001539843,0.007992145,0.001378834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002448043,"about_ca_system_score_gemma":0.00684594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01041675,"about_ca_topic_score_gemma":0.02567017,"domain_scores_codex":[0.9950827,0.0009015299,0.001824682,0.0002858044,0.001538147,0.0003670646],"domain_scores_gemma":[0.9907172,0.001735042,0.001364806,0.0003110435,0.004670177,0.00120178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002219509,0.0001657229,0.005633113,0.00237839,0.000114712,0.002564849,0.0005816577,0.0006636736,0.003500249,0.004029365,0.5752221,0.4049242],"study_design_scores_gemma":[0.0001184691,0.0001885425,0.01272324,0.005765958,0.0001401726,0.005635345,0.0002406938,0.0003488453,0.0009685049,0.00205397,0.9717441,0.00007215371],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.02035631,0.2471358,0.01379273,0.6462257,0.02897338,0.0007698943,0.001790234,0.000616496,0.04033941],"genre_scores_gemma":[0.1427043,0.3260991,0.06290568,0.3668664,0.05603644,0.001363583,0.007134729,0.0006971573,0.03619263],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01041675,"threshold_uncertainty_score":0.03167039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02982384085572492,"score_gpt":0.2775194712061712,"score_spread":0.2476956303504463,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}