{"id":"W2083076878","doi":"10.1371/journal.ppat.1001140","title":"Gene Annotation and Drug Target Discovery in Candida albicans with a Tagged Transposon Mutant Collection","year":2010,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Human Genome Research Institute; Canadian Institutes of Health Research; Centers for Disease Control and Prevention; National Institutes of Health","keywords":"Genetic screen; Candida albicans; Haploinsufficiency; Biology; Corpus albicans; Mutant; Gene; Genetics; Antifungal drug; Transposable element; Mutation; Phenotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001614478,0.0001315148,0.0002450489,0.00009098843,0.00008385578,0.00002026664,0.00002946543,0.00007193659,0.00004867169],"category_scores_gemma":[0.00007013068,0.0001013764,0.00003609218,0.000274239,0.00008997405,0.0001376589,0.000005121287,0.0002586241,0.000002313211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005435262,"about_ca_system_score_gemma":0.0001603262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002430274,"about_ca_topic_score_gemma":0.0146786,"domain_scores_codex":[0.9990353,0.00003984834,0.0001890129,0.0003081823,0.0002189629,0.000208718],"domain_scores_gemma":[0.9995509,0.00004518404,0.00004754097,0.0001877151,0.00006734943,0.0001013437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005858826,0.0001584129,0.4383268,0.00005247406,0.00001697339,0.00007531809,0.001216901,0.000002305655,0.5593741,0.00001435897,0.00001130415,0.0001651597],"study_design_scores_gemma":[0.001786497,0.0002900216,0.8744515,0.00008989221,0.0001046032,0.00003190169,0.0006064291,0.0005243734,0.1217909,0.00006003881,0.00009140598,0.0001723855],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982474,0.00005804972,0.0002997639,0.0004153977,0.00005142476,0.0004809544,0.00009089857,0.00003118584,0.000324927],"genre_scores_gemma":[0.9976145,0.00005626358,0.001551476,0.00009884331,0.00005751663,0.00003464523,0.00006391886,0.00001877399,0.0005040306],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4375832,"threshold_uncertainty_score":0.8191001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007438158958430965,"score_gpt":0.2216186878171901,"score_spread":0.2141805288587591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}