{"id":"W2083076878","doi":"10.1371/journal.ppat.1001140","title":"Gene Annotation and Drug Target Discovery in Candida albicans with a Tagged Transposon Mutant Collection","year":2010,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Human Genome Research Institute; Canadian Institutes of Health Research; Centers for Disease Control and Prevention; National Institutes of Health","keywords":"Genetic screen; Candida albicans; Haploinsufficiency; Biology; Corpus albicans; Mutant; Gene; Genetics; Antifungal drug; Transposable element; Mutation; Phenotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004116801,0.0005995833,0.0008446352,0.001199411,0.0003493798,0.0005179175,0.0005695867,0.0004298044,0.001410044],"category_scores_gemma":[0.0003881982,0.0003109435,0.0006061023,0.001383403,0.0002174513,0.000177887,0.0003420304,0.0006629298,0.0007405652],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005360957,"about_ca_system_score_gemma":0.0009285826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002859032,"about_ca_topic_score_gemma":0.005990427,"domain_scores_codex":[0.9996439,0.00003145188,0.00005194855,0.00005880213,0.0001854433,0.00002837931],"domain_scores_gemma":[0.9997934,0.00005173017,0.00003945186,0.00003305847,0.00004890778,0.00003360802],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001242766,0.00004712809,0.0003897273,0.00008024606,0.00001552492,0.0001818594,0.00001558745,0.0004349629,0.9923121,0.000120158,0.0003074692,0.005970876],"study_design_scores_gemma":[0.00009865871,0.0006642547,0.006341742,0.00002660643,0.0001377657,0.001719125,0.00006776337,0.006576671,0.9639114,0.0001425449,0.02027418,0.00003939875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9107274,0.00495962,0.04655502,0.0006753555,0.0001186703,0.001022075,0.02532779,0.004192679,0.00642131],"genre_scores_gemma":[0.7655601,0.007372534,0.1534862,0.000599882,0.00004399424,0.0006234747,0.05968482,0.0007609778,0.01186802],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002859032,"threshold_uncertainty_score":0.005684853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007438158958430965,"score_gpt":0.2216186878171901,"score_spread":0.2141805288587591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}