{"id":"W2083081748","doi":"10.1111/j.1462-2920.2005.00777.x","title":"Persister cells, the biofilm matrix and tolerance to metal cations in biofilm and planktonic <i>Pseudomonas aeruginosa</i>","year":2005,"lang":"en","type":"article","venue":"Environmental Microbiology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":210,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biofilm; Microbiology; Pseudomonas aeruginosa; Multidrug tolerance; Biology; Population; Bacteria; Minimum bactericidal concentration; Metal; Pseudomonas; Matrix (chemical analysis); Minimum inhibitory concentration; Chemistry; Antimicrobial; Chromatography; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000184569,0.0002808261,0.0002622343,0.0002402227,0.0002264922,0.0004499532,0.0001857879,0.0003832348,0.0007958774],"category_scores_gemma":[0.00023908,0.0001397156,0.000214462,0.0002030019,0.0001932086,0.0004097922,0.0002740813,0.00035427,0.0002100607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001869525,"about_ca_system_score_gemma":0.0002945671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002634888,"about_ca_topic_score_gemma":0.003059902,"domain_scores_codex":[0.9998385,0.00001703109,0.00001535379,0.00003530704,0.0000604312,0.0000333483],"domain_scores_gemma":[0.9997951,0.00003531333,0.00005588661,0.0000148301,0.00006699284,0.0000318269],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004384158,0.00001173768,0.00134739,0.00004057596,0.000002435145,0.00007824914,0.00007822458,0.0000125427,0.9972425,0.00003278019,0.00001548289,0.00109437],"study_design_scores_gemma":[0.00001628331,0.001414326,0.1171085,0.0000254079,0.00004899752,0.001243227,0.0008554978,0.000715501,0.8732422,0.000170343,0.005136003,0.00002369318],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957519,0.001772562,0.001284534,0.00008488021,0.00001009456,0.0000256709,0.0002315026,0.00002053526,0.0008183194],"genre_scores_gemma":[0.9919017,0.001127094,0.003086234,0.00006207338,0.00001403416,0.00005772015,0.0006186114,0.00001281384,0.003119745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002634888,"threshold_uncertainty_score":0.005239069,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004194396957218095,"score_gpt":0.1958253179693369,"score_spread":0.1916309210121188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}