{"id":"W2083143220","doi":"10.1002/pmic.201100471","title":"Strategies for membrane interaction proteomics: No mass spectrometry required","year":2012,"lang":"en","type":"review","venue":"PROTEOMICS","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Interactome; Proteomics; Bimolecular fluorescence complementation; Membrane protein; Chemistry; Protein–protein interaction; Membrane; Mass spectrometry; Cell biology; Cell membrane; Biology; Biochemistry; Computational biology; Yeast; Chromatography; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001765333,0.001378544,0.002184592,0.001850711,0.0004154102,0.001750546,0.001920161,0.002127948,0.002853189],"category_scores_gemma":[0.0009236883,0.0006969121,0.0006146117,0.001790044,0.001280896,0.003996697,0.001381356,0.003446016,0.008467633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001000715,"about_ca_system_score_gemma":0.00103362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004216197,"about_ca_topic_score_gemma":0.0006314796,"domain_scores_codex":[0.999065,0.00014495,0.00004381907,0.0001858965,0.0005131734,0.00004711594],"domain_scores_gemma":[0.9994618,0.0001586851,0.00005189695,0.00008590242,0.0001865631,0.00005508345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001291312,0.0001383708,0.0002922806,0.01042379,0.0001952066,0.0005279368,0.0001403838,0.0003697329,0.1841708,0.03457029,0.03236295,0.7366792],"study_design_scores_gemma":[0.00001570012,0.000116402,0.0005150422,0.0008195777,0.00006886115,0.002651865,0.00009526223,0.0004615971,0.04580569,0.01039234,0.9390043,0.00005342947],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001987665,0.9041032,0.07135258,0.004204342,0.001891872,0.00009431483,0.0002249095,0.0005322894,0.01560897],"genre_scores_gemma":[0.009668122,0.8952355,0.0745119,0.003592462,0.0008080765,0.0001677342,0.0004547837,0.000147473,0.015414],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002853189,"threshold_uncertainty_score":0.009544849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04417266172267056,"score_gpt":0.3252422566459482,"score_spread":0.2810695949232777,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}