{"id":"W2083241637","doi":"10.1074/jbc.m409579200","title":"The Nuclear Tyrosine Kinase BRK/Sik Phosphorylates and Inhibits the RNA-binding Activities of the Sam68-like Mammalian Proteins SLM-1 and SLM-2","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"RNA-binding protein; Phosphorylation; RNA; Gene expression; Cell biology; RNA splicing; Messenger RNA; Kinase; Biology; Chemistry; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000842174,0.0004257705,0.0001884775,0.0001686095,0.000112491,0.0001753266,0.000172356,0.000131743,0.001288104],"category_scores_gemma":[0.00009632453,0.0001392037,0.0002323454,0.000119908,0.0001827131,0.0001504803,0.0001647466,0.0003139431,0.0004840829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002018467,"about_ca_system_score_gemma":0.0001421683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002406984,"about_ca_topic_score_gemma":0.0005634339,"domain_scores_codex":[0.9999138,0.00001278469,0.00000627581,0.00001875381,0.00002355168,0.00002470837],"domain_scores_gemma":[0.9999352,0.000008245515,0.00002654718,0.000007442073,0.000005262008,0.00001731397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004963565,0.000004690707,0.0000959412,0.0000341737,0.000002823703,0.0000143124,0.000003690278,0.00002608434,0.9989618,0.00003970731,0.00001889991,0.000748263],"study_design_scores_gemma":[0.00002929677,0.0003050943,0.00654614,0.000007114718,0.00001511013,0.0002805815,0.00001376307,0.0008678825,0.9892785,0.00004902792,0.002603734,0.000003790238],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855703,0.008710895,0.003124624,0.0001022854,0.00004406599,0.00001325656,0.0002314484,0.0001902757,0.002012811],"genre_scores_gemma":[0.994006,0.001928392,0.001488861,0.00003184599,0.00001253258,0.00001776402,0.0004777689,0.00002156172,0.002015134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001288104,"threshold_uncertainty_score":0.004309177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01146214472696029,"score_gpt":0.2340042125357964,"score_spread":0.2225420678088361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}