{"id":"W2083254788","doi":"10.1016/j.neuron.2007.12.002","title":"Structures of Neuroligin-1 and the Neuroligin-1/Neurexin-1β Complex Reveal Specific Protein-Protein and Protein-Ca2+ Interactions","year":2007,"lang":"en","type":"article","venue":"Neuron","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":206,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Lawrence Berkeley National Laboratory; Basic Energy Sciences; Canadian Institutes of Health Research; National Institute of Mental Health; U.S. Department of Energy","keywords":"Neurexin; Neuroligin; Heterotetramer; Cell biology; Biology; Biophysics; Chemistry; Biochemistry; Protein subunit; Receptor; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007167525,0.0004550331,0.0004968574,0.0003994846,0.0007344178,0.0002056974,0.0008592072,0.00008662708,0.0000718903],"category_scores_gemma":[0.0008060107,0.0003397224,0.0001226081,0.000843751,0.002607274,0.0004171813,0.0005951887,0.001322476,0.00002229954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001857311,"about_ca_system_score_gemma":0.00006675356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000292879,"about_ca_topic_score_gemma":0.000007906483,"domain_scores_codex":[0.9951953,0.001036865,0.0006953861,0.00127995,0.0008627852,0.0009296706],"domain_scores_gemma":[0.9976264,0.0008843212,0.0003513446,0.0007122483,0.00009442493,0.0003312219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001335826,0.0001006809,0.0001463266,0.00006527668,0.00000322719,0.000330054,0.0001170817,0.000005289645,0.9893527,0.006137839,0.0003721775,0.002033545],"study_design_scores_gemma":[0.002243021,0.0006911163,0.008509759,0.00002506375,0.00001659912,0.0006389889,0.00002253151,0.0002673941,0.9662231,0.001731389,0.01933958,0.0002914594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906815,0.00007862333,0.00003858559,0.004035642,0.0004068383,0.002892839,0.00002866679,0.0001216106,0.001715642],"genre_scores_gemma":[0.9954165,0.0001061477,0.00006009927,0.002667753,0.000202688,0.00009973669,6.011679e-7,0.00006719649,0.00137923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02312957,"threshold_uncertainty_score":0.9999055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0606950858768967,"score_gpt":0.3410007851784411,"score_spread":0.2803056993015444,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}