{"id":"W2083287104","doi":"10.1016/j.aquatox.2010.01.002","title":"Effects of pulp and paper mill effluent extractives on aromatase CYP19a gene expression and sex steroid levels in juvenile triploid rainbow trout","year":2010,"lang":"en","type":"article","venue":"Aquatic Toxicology","topic":"Reproductive biology and impacts on aquatic species","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Environment and Climate Change Canada; University of Guelph; Ontario Tech University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Rainbow trout; Juvenile; Aromatase; Paper mill; Effluent; Biology; Fishery; Sex steroid; Endocrinology; Internal medicine; Steroid; Fish <Actinopterygii>; Ecology; Environmental engineering; Genetics; Hormone; Environmental science; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"},{"model":"gpt","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"high","status":"direct model label, unvalidated"}],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001059111,0.0002624972,0.0002514792,0.0002052527,0.0002071658,0.0003542541,0.0001796514,0.0003072713,0.002028328],"category_scores_gemma":[0.0002206352,0.0002328522,0.0003109432,0.0001602827,0.0003903634,0.0003379485,0.0002511954,0.0005661842,0.0002230496],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004668496,"about_ca_system_score_gemma":0.0003739958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005420346,"about_ca_topic_score_gemma":0.01015007,"domain_scores_codex":[0.9998672,0.0000126871,0.00001319519,0.00004174259,0.00002313886,0.000041968],"domain_scores_gemma":[0.9997284,0.00006794019,0.00005430216,0.00002270232,0.00003469251,0.00009190756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003732095,0.0001603576,0.002851549,0.0000262754,0.00002861535,0.000100484,0.00005970688,0.0001282824,0.9911451,0.00003921839,0.00004963015,0.00167867],"study_design_scores_gemma":[0.0001276941,0.005037515,0.1120745,0.000006261237,0.0001006004,0.0001790868,0.0003929834,0.0008811523,0.8802642,0.0000934745,0.0008151705,0.00002727287],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994829,0.00006445998,0.0001072118,0.00002019046,0.000006844341,0.000003274044,0.000142864,0.000004942853,0.0001673667],"genre_scores_gemma":[0.9944907,0.0001356126,0.0002408184,0.00005401432,0.000005889889,0.00001471128,0.000365661,0.00001077961,0.004681661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005420346,"threshold_uncertainty_score":0.01077759,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009150490683242241,"score_gpt":0.2561229471527002,"score_spread":0.246972456469458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}