{"id":"W2083322686","doi":"10.1038/nrm2789","title":"35 years later, mRNA caps still matter","year":2009,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Messenger RNA; Biology; Computational biology; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001598389,0.0009946853,0.001328837,0.0008609347,0.0008035701,0.002290919,0.000816164,0.003327024,0.005752736],"category_scores_gemma":[0.002280087,0.0003970295,0.0004770494,0.001190212,0.002811964,0.003923167,0.001711321,0.004038638,0.005117629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002084192,"about_ca_system_score_gemma":0.00133688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001961815,"about_ca_topic_score_gemma":0.00279331,"domain_scores_codex":[0.9996324,0.00006174563,0.00003858345,0.0001283863,0.00009718305,0.00004163289],"domain_scores_gemma":[0.9990925,0.0005233626,0.0000542906,0.00006817442,0.0002010152,0.00006068603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003437764,0.00005867466,0.0002886005,0.004475143,0.00007600093,0.0005494155,0.0002858755,0.0008197766,0.01109053,0.1081774,0.1131642,0.7606707],"study_design_scores_gemma":[0.000009058537,0.0000237536,0.0001385335,0.0003032818,0.0000129775,0.0002514429,0.00004897041,0.00005013573,0.002378939,0.005170033,0.9915986,0.00001433151],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007711892,0.9730198,0.002664915,0.006161925,0.008266621,0.00001301964,0.00008224319,0.00004889217,0.008971403],"genre_scores_gemma":[0.01087766,0.9388997,0.001874944,0.01242094,0.004378627,0.00004193496,0.0001475773,0.00005274932,0.03130588],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005752736,"threshold_uncertainty_score":0.01924485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01487178704546348,"score_gpt":0.3152114294062243,"score_spread":0.3003396423607608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}