{"id":"W2083342137","doi":"10.1016/s0169-328x(00)00120-0","title":"The splice variant D3nf reduces ligand binding to the D3 dopamine receptor: evidence for heterooligomerization","year":2000,"lang":"en","type":"article","venue":"Molecular Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health; Canada Research Chairs; University of Toronto","funders":"","keywords":"Biology; splice; Dopamine; Alternative splicing; Receptor; Ligand (biochemistry); Neuroscience; Dopamine receptor; Genetics; Gene; Gene isoform","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002467369,0.0002852771,0.0003363255,0.0002713675,0.0003709918,0.0004677302,0.000429692,0.0005100048,0.002711654],"category_scores_gemma":[0.0003011479,0.0002090056,0.0004373269,0.0001787298,0.0005248812,0.0002859982,0.0002624652,0.0008671515,0.0007409408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005009314,"about_ca_system_score_gemma":0.0002840992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002344804,"about_ca_topic_score_gemma":0.002105481,"domain_scores_codex":[0.9996926,0.00004849323,0.00003412921,0.00006839248,0.00007543073,0.00008110608],"domain_scores_gemma":[0.9995831,0.0001110819,0.00008190913,0.00009267599,0.0000343902,0.00009688169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001314834,0.00002753822,0.0001006509,0.000006032049,0.000006837737,0.00003523791,0.00001057784,0.00002556091,0.9991224,0.0001517681,0.00002360321,0.0003582749],"study_design_scores_gemma":[0.00004435456,0.0002022502,0.005266865,0.000003668154,0.00002539007,0.0007085699,0.00007380343,0.0006678781,0.991387,0.0003057235,0.001306066,0.000008477738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962935,0.00047005,0.001737508,0.0001708611,0.00003872751,0.000009818255,0.0003188266,0.00004437621,0.0009162949],"genre_scores_gemma":[0.9961367,0.000252095,0.001189932,0.0001478698,0.00001696004,0.00001619604,0.0004664837,0.00009628643,0.001677469],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002711654,"threshold_uncertainty_score":0.00907141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06195582749295415,"score_gpt":0.3779842600762683,"score_spread":0.3160284325833141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}