{"id":"W2083355262","doi":"10.1007/s00262-015-1657-9","title":"Role of NKG2D, DNAM-1 and natural cytotoxicity receptors in cytotoxicity toward rhabdomyosarcoma cell lines mediated by resting and IL-15-activated human natural killer cells","year":2015,"lang":"en","type":"article","venue":"Cancer Immunology Immunotherapy","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Stichting Kinderen Kankervrij; KWF Kankerbestrijding","keywords":"NKG2D; Cytotoxicity; Cytolysis; Lymphokine-activated killer cell; Immunotherapy; Natural killer cell; Biology; dNaM; Cancer research; NK-92; Immunology; Cell biology; Interleukin 21; T cell; In vitro; Immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003830069,0.0004288917,0.0003610956,0.000199872,0.0001044349,0.0003775471,0.0002751537,0.0003597193,0.0007010508],"category_scores_gemma":[0.0002471443,0.0001560865,0.0002772673,0.0000840478,0.0003680838,0.0003285464,0.0003210852,0.0004002824,0.0003254976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002483174,"about_ca_system_score_gemma":0.0002921673,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000333384,"about_ca_topic_score_gemma":0.0003593087,"domain_scores_codex":[0.9996086,0.0001594963,0.00004384998,0.00003952741,0.00006480724,0.00008369415],"domain_scores_gemma":[0.9998193,0.00006178664,0.0000352241,0.00003081239,0.00001747239,0.000035329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007493102,0.0001051628,0.002053071,0.00009078235,0.0000131628,0.0002255046,0.00006293211,0.0003175079,0.9930276,0.0001860248,0.00002603841,0.003142809],"study_design_scores_gemma":[0.0001571258,0.002407552,0.03295801,0.00002408552,0.00006677081,0.001650123,0.0001488485,0.00268511,0.9580052,0.0001692752,0.001715011,0.00001281496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964429,0.001988114,0.0007031865,0.00003150847,0.000005750653,0.00002376908,0.00008107575,0.00002112432,0.0007027028],"genre_scores_gemma":[0.9981505,0.0005264166,0.0005501617,0.00002441193,0.000004702949,0.00003758663,0.0001784368,0.000003529014,0.0005240878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007010508,"threshold_uncertainty_score":0.002345204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01320296510246764,"score_gpt":0.2531609153311134,"score_spread":0.2399579502286458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}