{"id":"W2083385434","doi":"10.1016/j.ijrobp.2013.06.412","title":"Results of a Phase 2 Clinical Trial of Neo-Adjuvant Temozolomide (TMZ), Followed by Concurrent TMZ and Hypofractionated Accelerated External Beam Radiation Therapy (Ac-EBRT) With Limited Margins, and Adjuvant TMZ for Patients With Glioblastoma Multiforme (GBM)","year":2013,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Temozolomide; Adjuvant; Concomitant; Radiation therapy; Nuclear medicine; Phases of clinical research; External beam radiotherapy; Surgery; Toxicity; Internal medicine; Brachytherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002243014,0.001919469,0.002625952,0.0004787222,0.0004932847,0.0008399592,0.0009033577,0.001462162,0.002906546],"category_scores_gemma":[0.001441951,0.0007114648,0.001682694,0.0004708545,0.001147724,0.001198366,0.0003979508,0.00354665,0.0006162846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001053155,"about_ca_system_score_gemma":0.002139234,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001634978,"about_ca_topic_score_gemma":0.004221726,"domain_scores_codex":[0.9994876,0.0002366988,0.00002738332,0.00009825964,0.00003758738,0.0001124521],"domain_scores_gemma":[0.9990671,0.000185378,0.0001446426,0.00007777833,0.00006007636,0.0004650719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8511537,0.07618055,0.002780187,0.0004347659,0.001291569,0.00009546222,0.00025541,0.002479028,0.01816078,0.0002190161,0.002365715,0.04458384],"study_design_scores_gemma":[0.6095834,0.3779782,0.006867597,0.00002375754,0.0007955923,0.0001049497,0.00004534729,0.0007927868,0.001997976,0.0002483797,0.001533013,0.00002892806],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904829,0.002335167,0.0005904189,0.000739762,0.0003076358,0.002563,0.001344643,0.00007201319,0.001564519],"genre_scores_gemma":[0.9837499,0.002476712,0.002254635,0.001214272,0.0002828042,0.003487872,0.003737448,0.00005281163,0.002743303],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002906546,"threshold_uncertainty_score":0.01186234,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03017419836798036,"score_gpt":0.3575175209540324,"score_spread":0.327343322586052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}