{"id":"W2083412868","doi":"10.1016/j.chom.2008.12.011","title":"Shigella Induces Mitochondrial Dysfunction and Cell Death in Nonmyleoid Cells","year":2009,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":154,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Cell biology; Shigella; Programmed cell death; Mitochondrion; Inflammasome; Shigella flexneri; Signal transduction; Intracellular; Apoptosis; Oxidative stress; Microbiology; Immunology; Inflammation; Biochemistry; Bacteria; Escherichia coli; Genetics; Salmonella","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001814494,0.0002427228,0.0002774816,0.0002235051,0.0001516034,0.00004101624,0.0001584984,0.0004102834,0.0002603518],"category_scores_gemma":[0.00001289401,0.0002352218,0.00007075581,0.0001523561,0.00006900149,0.0001812457,0.00005042424,0.0003781451,0.0008784618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005514037,"about_ca_system_score_gemma":0.0000611656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008765754,"about_ca_topic_score_gemma":0.00001328977,"domain_scores_codex":[0.99862,0.0001892892,0.0003756986,0.0003707639,0.00003133392,0.0004129145],"domain_scores_gemma":[0.9994638,0.00007895475,0.0001368284,0.0002555625,0.00003934251,0.00002550986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003787249,0.0001575642,0.0001913246,0.00001761275,0.000008288082,0.00000813631,0.0007036822,0.000004307267,0.9944562,0.0000267538,0.002370176,0.001677188],"study_design_scores_gemma":[0.002146018,0.0002953323,0.007360005,0.00003042336,0.0000233532,0.00002066708,0.0001656611,0.000002534123,0.9559991,0.00004242888,0.03366309,0.0002513543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886779,0.004294925,0.00006848461,0.000154072,0.001037637,0.0003288109,0.00000605869,0.00004901139,0.005383076],"genre_scores_gemma":[0.9921492,0.0005787501,0.0001620004,0.0002530836,0.00008051687,0.000007507144,0.00008633895,0.00001663621,0.006665905],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03845711,"threshold_uncertainty_score":0.9998994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006503378628795673,"score_gpt":0.2044707162613187,"score_spread":0.197967337632523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}