{"id":"W2083424582","doi":"10.1021/ac0506480","title":"Entrapment of Fluorescent Signaling DNA Aptamers in Sol−Gel-Derived Silica","year":2005,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Aptamer; Chemistry; Fluorescein; Biophysics; Fluorescence; DNA; Analyte; Combinatorial chemistry; Biochemistry; Chromatography; Molecular biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002010128,0.0004562087,0.0002324726,0.0002136805,0.0001430106,0.0002855163,0.0002366729,0.0002971474,0.00038298],"category_scores_gemma":[0.000195139,0.0002229044,0.0003373953,0.0001171941,0.0002605506,0.0002153188,0.000245516,0.000302251,0.0003616731],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002962321,"about_ca_system_score_gemma":0.0002629328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006893635,"about_ca_topic_score_gemma":0.001487141,"domain_scores_codex":[0.9998758,0.00001078787,0.000009955354,0.00003031439,0.0000466282,0.00002642994],"domain_scores_gemma":[0.9998726,0.00003858294,0.00002772389,0.00001330319,0.00002703707,0.00002073366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000006225824,0.000004121263,0.00002853285,0.00001864013,0.000002000449,0.0000204673,0.00001342351,0.00008135838,0.9992453,0.0000356285,0.00000518792,0.0005390772],"study_design_scores_gemma":[0.000002134758,0.00006257398,0.0002014868,0.000001685249,0.000003981336,0.00003017814,0.000008287876,0.0005806333,0.9985735,0.00001218034,0.0005205074,0.000002769387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800062,0.001051271,0.01713288,0.00006166848,0.0000485885,0.00007528183,0.00007987583,0.0002099354,0.001334266],"genre_scores_gemma":[0.9730127,0.0008494888,0.02249369,0.00005913021,0.00001979247,0.00005118665,0.0001532984,0.00005665792,0.00330409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006893635,"threshold_uncertainty_score":0.002149343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007963649496072348,"score_gpt":0.2596485127060357,"score_spread":0.2516848632099633,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}