{"id":"W2083430366","doi":"10.4161/cam.1.3.4984","title":"P-selectin Cross-links PSGL-1 and Enhances Neutrophil Adhesion to Fibrinogen and ICAM-1 in a Src Kinase-Dependent, but GPCR-Independent Mechanism","year":2007,"lang":"en","type":"article","venue":"Cell Adhesion & Migration","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Cell biology; Cell adhesion molecule; Integrin; Cell adhesion; Proto-oncogene tyrosine-protein kinase Src; Platelet activation; Chemistry; P-selectin; Signal transduction; Biology; Platelet; Adhesion; Receptor; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001240539,0.0004308814,0.0005224867,0.0007903064,0.0002525459,0.0001708179,0.0001872911,0.0005460715,0.0001919955],"category_scores_gemma":[0.0002547236,0.0003686057,0.0001063806,0.0006232932,0.00009717886,0.0002507215,0.0002732405,0.0008711573,0.0001964481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002954258,"about_ca_system_score_gemma":0.0001469592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006180254,"about_ca_topic_score_gemma":0.001398424,"domain_scores_codex":[0.9960565,0.0001681395,0.0008124797,0.001116091,0.001054323,0.0007924752],"domain_scores_gemma":[0.9981025,0.0002573721,0.0001854795,0.0004963127,0.0002746399,0.0006837063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001062065,0.0002514819,0.01772338,0.000198117,0.00001025889,0.0002844172,0.0005349764,0.000005893062,0.9715228,0.00008260996,0.00023796,0.008086062],"study_design_scores_gemma":[0.002145774,0.001232284,0.1103999,0.0001693502,0.00003585494,0.00009161148,0.0004146089,0.0003779934,0.8832901,0.0003632064,0.001127816,0.0003515272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945297,0.0008338474,0.001298395,0.0007933893,0.0001560084,0.001441027,0.000007314366,0.0001032951,0.0008370423],"genre_scores_gemma":[0.9907579,0.001101295,0.00216137,0.0004989719,0.0002100265,0.00005376013,0.0000464,0.00007375512,0.005096454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0926765,"threshold_uncertainty_score":0.9998766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0201138486702344,"score_gpt":0.3059214870487022,"score_spread":0.2858076383784678,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}