{"id":"W2083445077","doi":"10.1016/j.bone.2009.11.012","title":"Gene expression profile in osteoclasts from patients with Paget's disease of bone","year":2009,"lang":"en","type":"article","venue":"Bone","topic":"Bone health and treatments","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre hospitalier de l'Université Laval; Université Laval; Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Protein Data Bank (RCSB PDB); Paget's disease of bone; Gene; Biology; Osteoclast; Genetics; Bone resorption; Mutation; Gene expression; Candidate gene; Bone remodeling; Cancer research; Medicine; Pathology; In vitro; Disease; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003476266,0.000117157,0.0002861597,0.00007753947,0.00002267176,0.00000266041,0.00002137766,0.00004816339,0.0000948847],"category_scores_gemma":[0.00003120133,0.00008280656,0.00003088276,0.0001178823,0.00002018914,0.00006028635,0.00001251066,0.00008114044,0.00003104802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004473412,"about_ca_system_score_gemma":0.00009519702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001247121,"about_ca_topic_score_gemma":0.00001796197,"domain_scores_codex":[0.9990398,0.00002358229,0.0002519156,0.0002122301,0.0002621876,0.0002102841],"domain_scores_gemma":[0.9992874,0.00001675009,0.0001010343,0.0002661886,0.00004908133,0.0002794917],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004341832,0.002405003,0.9663647,0.00006906146,0.00001238266,0.0002875199,0.000159565,0.000001318539,0.006886622,0.00000376599,0.000427498,0.01904077],"study_design_scores_gemma":[0.0077212,0.0006255592,0.978088,0.0003776036,0.0000415333,0.000001099149,0.000007860404,0.00001185317,0.01288863,0.00005781711,0.0001052376,0.00007356701],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979862,0.0005620504,0.000008618718,0.0003118205,0.00003100757,0.0006286464,0.0000895802,0.00002078727,0.0003612934],"genre_scores_gemma":[0.9964136,0.00001356192,0.002556837,0.0002528258,0.00002212294,0.00002560737,0.0003461384,0.00001245976,0.0003568437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0189672,"threshold_uncertainty_score":0.3376754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00909397446819668,"score_gpt":0.2466037781429908,"score_spread":0.2375098036747941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}