{"id":"W2083486056","doi":"10.1002/mas.10081","title":"Investigation of intact protein complexes by mass spectrometry","year":2004,"lang":"en","type":"review","venue":"Mass Spectrometry Reviews","topic":"Mass Spectrometry Techniques and Applications","field":"Chemistry","cited_by":583,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Sandia National Laboratories; Università degli Studi di Pavia; Wageningen University and Research; Universiteit Utrecht; Syddansk Universitet; University of Cambridge; Universiteit van Amsterdam; University of Warwick; University of Alberta","keywords":"Chemistry; Mass spectrometry; Cooperativity; Electrospray ionization; Cofactor; Covalent bond; Protein subunit; Nanotechnology; Proteomics; Computational biology; Chromatography; Biochemistry; Organic chemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000479196,0.001189407,0.001117241,0.002352034,0.0002825934,0.0008130074,0.0009602706,0.001184738,0.00321301],"category_scores_gemma":[0.0003196714,0.0003727459,0.0003317619,0.001564851,0.000577712,0.00132343,0.000526504,0.001067729,0.005860847],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006769765,"about_ca_system_score_gemma":0.0003711934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003576267,"about_ca_topic_score_gemma":0.0003882876,"domain_scores_codex":[0.9996686,0.00003867688,0.00001653577,0.0000887309,0.0001666695,0.00002071629],"domain_scores_gemma":[0.9998615,0.00003705377,0.00002290243,0.00001407101,0.00005267351,0.00001178434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001212207,0.00009016316,0.0006501202,0.00620017,0.0001199046,0.0007259217,0.000101365,0.0004357248,0.4220349,0.01338742,0.02169087,0.5344422],"study_design_scores_gemma":[0.00002010785,0.0002149264,0.002667106,0.0005838819,0.00007784237,0.004590095,0.00008275261,0.001162273,0.2832571,0.006528069,0.7007629,0.00005296657],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006178248,0.9178061,0.0475004,0.0008913781,0.000980486,0.000108946,0.0003508732,0.0005577597,0.02562577],"genre_scores_gemma":[0.03672029,0.8799927,0.04864112,0.001143692,0.0009004826,0.0002245319,0.000734724,0.00009576126,0.0315468],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00321301,"threshold_uncertainty_score":0.01074862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05176259386993178,"score_gpt":0.3175040214228875,"score_spread":0.2657414275529557,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}