{"id":"W2083541958","doi":"10.1016/j.vaccine.2012.09.067","title":"Heteroclitic peptides enhance human immunodeficiency virus-specific CD8+ T cell responses","year":2012,"lang":"en","type":"article","venue":"Vaccine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research; Canadian Foundation for AIDS Research; amfAR, The Foundation for AIDS Research","keywords":"Human leukocyte antigen; CD8; Virology; Biology; Immunology; Peptide vaccine; T cell; HIV vaccine; Cytotoxic T cell; Peptide; Antigen; HIV Antigens; Epitope; Virus; Immune system; Vaccination; Viral disease; Genetics; Vaccine trial; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027121,0.000739129,0.000469273,0.0003336294,0.0002332452,0.0004508136,0.0002457968,0.0006817442,0.003536899],"category_scores_gemma":[0.0002477331,0.0002289293,0.000270391,0.0001318388,0.0002581506,0.0004017144,0.0004251994,0.002002639,0.0007997295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001842847,"about_ca_system_score_gemma":0.0001818003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001386171,"about_ca_topic_score_gemma":0.0003922203,"domain_scores_codex":[0.9997174,0.00007846901,0.00001387327,0.00003568302,0.0000396953,0.0001149609],"domain_scores_gemma":[0.9997631,0.0001041043,0.00002170373,0.00003099313,0.00001435975,0.00006579769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003180839,0.002348542,0.0007524486,0.0001624296,0.00003472622,0.0001719341,0.00006642515,0.001697753,0.9710647,0.000367449,0.0005470509,0.01960563],"study_design_scores_gemma":[0.001492775,0.01407359,0.01041149,0.00004935773,0.0001035133,0.0007116873,0.0001609527,0.00512846,0.9618191,0.0005977704,0.005422832,0.00002859348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995068,0.000512994,0.0006531694,0.00006954953,0.00010525,0.0000756822,0.0000823208,0.00003819331,0.003394942],"genre_scores_gemma":[0.9960601,0.0003533771,0.0007143457,0.0001389094,0.0001159721,0.00005240074,0.0001761031,0.00001769889,0.002371099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003536899,"threshold_uncertainty_score":0.01183212,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02241592746179152,"score_gpt":0.2919540472006925,"score_spread":0.269538119738901,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}