{"id":"W2083547960","doi":"10.1097/01.jto.0000283087.71346.19","title":"PRS-02: Gefitinib (IRESSA) versus docetaxel in patients with locally advanced or metastatic non-small-cell lung cancer pre-treated with platinum-based chemotherapy: a randomized, open-label Phase III study (INTEREST)","year":2007,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Docetaxel; Gefitinib; Lung cancer; Internal medicine; Oncology; Tolerability; Hazard ratio; Population; Clinical endpoint; Randomized controlled trial; Performance status; Chemotherapy; Cancer; Epidermal growth factor receptor; Adverse effect; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001050073,0.0003935019,0.001753666,0.0003887992,0.00009752883,0.00004679487,0.0002783239,0.0001007809,0.0001672392],"category_scores_gemma":[0.00009353247,0.0002185029,0.00009145599,0.0005331655,0.0001394316,0.0002699073,0.00003930709,0.0004723415,0.000001366007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001111801,"about_ca_system_score_gemma":0.002272482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002812638,"about_ca_topic_score_gemma":0.002623875,"domain_scores_codex":[0.9972888,0.0002709989,0.001156471,0.0003691488,0.0004440911,0.0004705451],"domain_scores_gemma":[0.9965464,0.0007078135,0.001453449,0.0002839726,0.0007116934,0.0002967043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.894408,0.0214986,0.02477028,0.0001527592,0.00273389,0.001765167,0.00200411,0.0005131624,0.0001325604,0.000001005947,0.00009700086,0.05192347],"study_design_scores_gemma":[0.9345385,0.04602397,0.009231718,0.001103358,0.005347377,0.00006102274,0.001331091,0.0007962293,0.001108106,0.000002461525,0.0001735318,0.0002825736],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892774,0.0002876396,0.002755102,0.0004081683,0.0002149323,0.006333649,0.00002539168,0.00001717306,0.0006805283],"genre_scores_gemma":[0.9843129,0.00003779197,0.01408808,0.0004493367,0.00006994978,0.0003015615,0.0000280416,0.00006555468,0.0006467641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05164089,"threshold_uncertainty_score":0.8910288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03308441330919291,"score_gpt":0.4527919738624805,"score_spread":0.4197075605532876,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}