{"id":"W2083583664","doi":"10.1023/a:1026114501364","title":"Ligand-Induced Regulation of ERα and ERβ is Indicative of Human Breast Cancer Cell Proliferation","year":2003,"lang":"en","type":"article","venue":"Breast Cancer Research and Treatment","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Antiestrogen; Estrogen receptor; Tamoxifen; Cell growth; Genistein; Cancer research; Estrogen receptor alpha; Breast cancer; Estrogen; Estrogen receptor beta; Biology; Cell; Selective estrogen receptor modulator; Internal medicine; Endocrinology; Cell culture; MCF-7; Cancer; Medicine; Human breast; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002082023,0.0002263046,0.0001797836,0.0007895668,0.0002855177,0.0003251608,0.0001272342,0.0001776848,0.003211707],"category_scores_gemma":[0.0001866426,0.0001748092,0.0002146637,0.0005603189,0.0001889428,0.0001727546,0.0001679426,0.0004031755,0.000664808],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003067571,"about_ca_system_score_gemma":0.0001822823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005353119,"about_ca_topic_score_gemma":0.0008748815,"domain_scores_codex":[0.999778,0.0000686898,0.00001561434,0.00002781896,0.00005384013,0.00005600591],"domain_scores_gemma":[0.9998639,0.0000369152,0.00002090965,0.00001635739,0.00002984251,0.00003218444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004436284,0.00005766227,0.0007842131,0.0000376789,0.000006950128,0.00006586644,0.00002646828,0.00002926348,0.9960697,0.0001756319,0.00009981405,0.002203112],"study_design_scores_gemma":[0.00001622254,0.0004193524,0.02595344,0.000005474095,0.00001481921,0.0004993912,0.00006729314,0.0001838025,0.9690935,0.00007191094,0.003670572,0.000004306138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827879,0.006165027,0.003054577,0.0001535767,0.0000577191,0.00003823658,0.001271557,0.0001551023,0.006316245],"genre_scores_gemma":[0.9850947,0.002196813,0.00209013,0.00008761703,0.00003085747,0.00007815169,0.002633383,0.00002746165,0.007761007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003211707,"threshold_uncertainty_score":0.01074421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02277761949672809,"score_gpt":0.3351458927874194,"score_spread":0.3123682732906913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}