{"id":"W2083583664","doi":"10.1023/a:1026114501364","title":"Ligand-Induced Regulation of ERα and ERβ is Indicative of Human Breast Cancer Cell Proliferation","year":2003,"lang":"en","type":"article","venue":"Breast Cancer Research and Treatment","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Antiestrogen; Estrogen receptor; Tamoxifen; Cell growth; Genistein; Cancer research; Estrogen receptor alpha; Breast cancer; Estrogen; Estrogen receptor beta; Biology; Cell; Selective estrogen receptor modulator; Internal medicine; Endocrinology; Cell culture; MCF-7; Cancer; Medicine; Human breast; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001270056,0.0001129949,0.0001443581,0.00005363952,0.0001101237,0.00001164712,0.00003693779,0.0001154386,0.00003017832],"category_scores_gemma":[0.000004078181,0.00008547147,0.00003123861,0.00009902004,0.0001237339,0.000007556328,0.00002509531,0.0000599094,4.680799e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006192893,"about_ca_system_score_gemma":0.0001794063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00146154,"about_ca_topic_score_gemma":0.0001833287,"domain_scores_codex":[0.9991618,0.00009439452,0.0001393529,0.0002561663,0.0001647133,0.0001835927],"domain_scores_gemma":[0.9994444,0.000009584524,0.0001247452,0.0001461788,0.0001764434,0.00009863928],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003523282,0.0002836991,0.04675228,0.00005121729,0.0001733535,0.000001015864,0.0003690117,0.000002004521,0.9422634,0.0001442059,0.00009308676,0.009514366],"study_design_scores_gemma":[0.001309198,0.0008985313,0.1146979,0.00004531984,0.00002959836,0.00002125058,0.00009145271,0.0000082513,0.8827121,0.00006868087,0.00004571012,0.00007203219],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952577,0.003523858,0.000002017155,0.0001736943,0.00001318978,0.0003995766,0.0001520453,0.000002558097,0.0004753031],"genre_scores_gemma":[0.9962786,0.003161659,0.00001674898,0.0000076051,0.0000432317,0.0001255133,0.00003276087,0.00001171459,0.00032216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06794566,"threshold_uncertainty_score":0.3485425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02277761949672809,"score_gpt":0.3351458927874194,"score_spread":0.3123682732906913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}