{"id":"W2083643103","doi":"10.1371/journal.pone.0031176","title":"Establishment of Motor Neuron-V3 Interneuron Progenitor Domain Boundary in Ventral Spinal Cord Requires Groucho-Mediated Transcriptional Corepression","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Sonic hedgehog; Neuroscience; Progenitor cell; Biology; Interneuron; Spinal cord; Cell fate determination; Progenitor; Ventral nerve cord; Transcription factor; Motor neuron; Cell biology; Anatomy; Stem cell; Central nervous system; Signal transduction; Genetics; Inhibitory postsynaptic potential","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001060499,0.0002595529,0.0001596531,0.0001474569,0.0001344221,0.0002719697,0.0001924949,0.0002304142,0.0007220075],"category_scores_gemma":[0.0001098739,0.0001250504,0.0001920602,0.0000536095,0.0003401593,0.0001872071,0.0003737436,0.0004487382,0.000279327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002889197,"about_ca_system_score_gemma":0.0002443222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004369094,"about_ca_topic_score_gemma":0.0007031568,"domain_scores_codex":[0.9998916,0.00000920916,0.000007347885,0.00002894773,0.00002650015,0.0000363255],"domain_scores_gemma":[0.9998527,0.00002184769,0.00005525972,0.00001519312,0.00001015578,0.00004485985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003870165,0.000004501009,0.0001617232,0.00001310767,9.282344e-7,0.00004230361,0.000007417993,0.00002349255,0.9993248,0.0000875203,0.000005018768,0.0002904053],"study_design_scores_gemma":[0.00001061044,0.0001016988,0.009819861,0.000008814411,0.000006119239,0.0003318631,0.00003771329,0.0008091258,0.9880325,0.00006974705,0.0007693005,0.000002754367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952335,0.0004392901,0.003019219,0.00002928529,0.000005751369,0.00001642663,0.000102733,0.00005872408,0.001095213],"genre_scores_gemma":[0.996747,0.0002104416,0.001435821,0.00001918981,0.000002345949,0.00001945384,0.0002200746,0.00001871113,0.001326875],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007220075,"threshold_uncertainty_score":0.002415419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02753322767169654,"score_gpt":0.2512561852033358,"score_spread":0.2237229575316393,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}