{"id":"W2083643231","doi":"10.1021/ol050195l","title":"Enantioselective Direct Intermolecular Aldol Reactions with Enantiotopic Group Selectivity and Dynamic Kinetic Resolution","year":2005,"lang":"en","type":"article","venue":"Organic Letters","topic":"Asymmetric Synthesis and Catalysis","field":"Chemistry","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Chemistry; Enantioselective synthesis; Aldol reaction; Kinetic resolution; Selectivity; Decane; Stereocenter; Synthon; Adduct; Intermolecular force; Stereochemistry; Catalysis; Organic chemistry; Molecule","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000378568,0.001175491,0.0003354056,0.0003096319,0.0002757535,0.0004522857,0.0005380202,0.0002907546,0.002720076],"category_scores_gemma":[0.000234578,0.0003032156,0.0003036437,0.0002818424,0.0003336304,0.000447016,0.0005852267,0.0009182317,0.001515443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000365674,"about_ca_system_score_gemma":0.0002633628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000526316,"about_ca_topic_score_gemma":0.001161513,"domain_scores_codex":[0.999703,0.00003674027,0.00002558972,0.00005940608,0.00006847706,0.0001066643],"domain_scores_gemma":[0.9998634,0.00001826234,0.0000326667,0.00003015298,0.00002335497,0.00003216105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002241871,0.0001529398,0.0004523983,0.000244567,0.00007060551,0.0006898708,0.0001758306,0.001232298,0.9736531,0.002778328,0.0009922361,0.01933366],"study_design_scores_gemma":[0.00003465386,0.0001123441,0.0002545621,0.000003094544,0.00002295847,0.0004349365,0.00001627057,0.0005313163,0.9934035,0.0001335789,0.005041484,0.00001118055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8682702,0.004435303,0.08262729,0.0003584944,0.0003569102,0.000301711,0.001132538,0.001132972,0.04138461],"genre_scores_gemma":[0.9702489,0.002697613,0.01668798,0.00006341479,0.00005469847,0.0000724635,0.0006779215,0.0001167947,0.009380179],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002720076,"threshold_uncertainty_score":0.009099603,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00290549837239288,"score_gpt":0.1833865670349259,"score_spread":0.180481068662533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}