{"id":"W2083698768","doi":"10.1186/1471-213x-10-32","title":"Ectodermal Wnt6 is an early negative regulator of limb chondrogenesis in the chicken embryo","year":2010,"lang":"en","type":"article","venue":"BMC Developmental Biology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver Hospital and Health Sciences Centre; University of British Columbia","funders":"","keywords":"Chondrogenesis; Limb development; Ectoderm; Limb bud; Biology; Zone of polarizing activity; Mesenchyme; Apical ectodermal ridge; Anatomy; SOX9; Cell biology; Mesoderm; Wnt signaling pathway; Cartilage; Embryo; Embryogenesis; Genetics; Gene expression; Embryonic stem cell; Gene; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000403309,0.0002323013,0.000224088,0.00009968198,0.0001123475,0.00001208607,0.0004782368,0.0004277258,0.00009035942],"category_scores_gemma":[0.00006893124,0.0001766573,0.00008333837,0.0002135471,0.0003492931,0.00001803407,0.0001571712,0.0001659522,0.00002822286],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001537027,"about_ca_system_score_gemma":0.0002218609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005453816,"about_ca_topic_score_gemma":0.001093057,"domain_scores_codex":[0.9984927,0.0001980795,0.000388955,0.0004855898,0.0001027181,0.000331948],"domain_scores_gemma":[0.9994014,0.00004066947,0.0001404613,0.000295007,0.00005750217,0.00006499291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001633514,0.0000836344,0.2757173,0.000006503294,0.00003368242,9.331128e-7,0.0005537286,8.716302e-7,0.7208996,0.0002940063,0.00009092411,0.002155518],"study_design_scores_gemma":[0.00043856,0.0002018555,0.5435131,0.000003241805,0.000004494565,0.0000416285,0.0002653046,0.000004911329,0.453918,0.0003589044,0.001072158,0.0001778702],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982508,0.00009225511,0.00007933173,0.0001123599,0.0002820317,0.0003081495,0.00003820125,0.00001043041,0.0008263978],"genre_scores_gemma":[0.9921238,0.00002239639,0.006499898,0.0005488305,0.00009922986,0.00005448136,0.0003787301,0.00001617864,0.0002564928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2677958,"threshold_uncertainty_score":0.7203878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01318381799718813,"score_gpt":0.2559881026886334,"score_spread":0.2428042846914453,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}