{"id":"W2083714459","doi":"10.1074/jbc.m611327200","title":"The Scaffolding Adapter Gab1 Mediates Vascular Endothelial Growth Factor Signaling and Is Required for Endothelial Cell Migration and Capillary Formation","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Centre hospitalier de l'Université Laval","funders":"Institut Du Cancer de Montréal; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Cell biology; Adapter (computing); Signal transducing adaptor protein; Endothelial stem cell; Vascular endothelial growth factor; Vascular endothelial growth factor A; Vascular permeability; Vascular endothelial growth factor C; Chemistry; VEGF receptors; Signal transduction; Cancer research; Biology; Computer science; Biochemistry; Endocrinology; Computer hardware","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002330613,0.0001295806,0.0001515586,0.00001102639,0.0001492692,0.00004881496,0.00009586172,0.0001809851,0.000008687423],"category_scores_gemma":[0.00008269099,0.00007789057,0.0001495635,0.00002106348,0.00009072935,0.000011797,0.00003612636,0.00005653268,1.678985e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001428101,"about_ca_system_score_gemma":0.00002484073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006415793,"about_ca_topic_score_gemma":0.000002146318,"domain_scores_codex":[0.9992341,0.00002527726,0.0003219404,0.0001499569,0.0001056108,0.0001631295],"domain_scores_gemma":[0.9993899,0.00008792374,0.0002612198,0.00007085639,0.000134501,0.00005552874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001355471,0.00001504596,0.002308923,0.00003188975,0.00002673991,9.356525e-7,0.00002229214,0.000003814146,0.9965244,0.000006407405,0.0003485503,0.0005754514],"study_design_scores_gemma":[0.0006209543,0.000169866,0.000732303,0.00001531912,0.00002621158,0.00003497418,0.00008984566,0.00006474011,0.9875919,0.000240457,0.01030116,0.0001122282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894778,0.008920623,0.001176312,0.0001814253,0.00005873225,0.00008505263,0.00005135039,0.000003185954,0.00004549206],"genre_scores_gemma":[0.993533,0.004783839,0.0005074191,0.00008977546,0.000993653,0.000007415373,0.00002657819,0.000008974584,0.00004936005],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009952608,"threshold_uncertainty_score":0.3176285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01578931441103699,"score_gpt":0.2287622131715748,"score_spread":0.2129728987605378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}