{"id":"W2083757764","doi":"10.1074/jbc.m702112200","title":"Retinoic Acid-inducible Gene-I and Interferon-β Promoter Stimulator-1 Augment Proapoptotic Responses Following Mammalian Reovirus Infection via Interferon Regulatory Factor-3","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; McGill University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Vanderbilt-Ingram Cancer Center; National Cancer Institute; Vanderbilt University; Vanderbilt Diabetes Research and Training Center, Vanderbilt University Medical Center; Canadian Institutes of Health Research","keywords":"Interferon; Interferon regulatory factors; Biology; IRF1; Retinoic acid; Viral replication; Cell biology; Apoptosis; Cytokine; Transcription factor; Virology; Virus; Cell culture; Immunology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002444082,0.0004573495,0.0004792406,0.0003907184,0.0001365188,0.0004188611,0.0002797775,0.0003520763,0.001955961],"category_scores_gemma":[0.0002549904,0.0001793367,0.0007337827,0.0001496514,0.0002132669,0.0003572251,0.0003126164,0.001047289,0.0007035603],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003210837,"about_ca_system_score_gemma":0.0002534068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002586485,"about_ca_topic_score_gemma":0.0004848918,"domain_scores_codex":[0.9996618,0.00006095455,0.00002964789,0.00004640433,0.00007160029,0.0001295946],"domain_scores_gemma":[0.9997413,0.00005702038,0.00006723334,0.00004216457,0.00003095072,0.00006137542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002967496,0.00008216381,0.0002035403,0.00005171283,0.000009615193,0.00006036532,0.00002209665,0.00007249741,0.9971753,0.0001254301,0.00009009053,0.001810434],"study_design_scores_gemma":[0.00005452746,0.0007337941,0.005233691,0.00002008001,0.00003514141,0.0003673757,0.00007313371,0.0009172112,0.9880508,0.0001427666,0.004362357,0.00000918261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827316,0.00785829,0.004132553,0.0003248349,0.0001872458,0.0000941523,0.0004805475,0.000213831,0.003977007],"genre_scores_gemma":[0.9902741,0.002151794,0.00314015,0.0001876667,0.00004222115,0.00009079841,0.0008322449,0.00003497647,0.003245968],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001955961,"threshold_uncertainty_score":0.006543338,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05274982409317247,"score_gpt":0.3362022658608636,"score_spread":0.2834524417676911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}