{"id":"W2083809717","doi":"10.1155/2012/493670","title":"Tau and Caspase 3 as Targets for Neuroprotection","year":2012,"lang":"en","type":"article","venue":"International Journal of Alzheimer s Disease","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Tel Aviv University; Canadian Friends of Tel Aviv University","keywords":"Neuroprotection; Hyperphosphorylation; Caspase; Apoptosis; Programmed cell death; Nap; Neurodegeneration; Cell biology; Caspase 3; Caspase 2; Mitochondrion; Cytochrome c; Tau protein; Caspase-9; Viability assay; Pharmacology; Biology; Medicine; Biochemistry; Neuroscience; Alzheimer's disease; Kinase; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003803921,0.000570484,0.0005191853,0.0006053858,0.0002139793,0.0005558303,0.0003012504,0.0006918632,0.001412016],"category_scores_gemma":[0.0001940229,0.0001604702,0.0003454972,0.0003018847,0.0003268793,0.0008235046,0.0003214608,0.000939208,0.0003870993],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004598423,"about_ca_system_score_gemma":0.0002682676,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000182684,"about_ca_topic_score_gemma":0.0004591719,"domain_scores_codex":[0.9998173,0.00004661631,0.00001739736,0.00003289013,0.00004589801,0.00003985993],"domain_scores_gemma":[0.9998866,0.00001790558,0.00003089479,0.000006721962,0.00003193431,0.00002595694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001696559,0.0001883963,0.0006452827,0.0008883204,0.00004038047,0.0004588456,0.00006716565,0.0004459962,0.9332254,0.001905216,0.0004736537,0.05996484],"study_design_scores_gemma":[0.0005024612,0.004654207,0.008867732,0.0002116158,0.0001693936,0.002886761,0.0001705753,0.00297325,0.9449534,0.005931449,0.02863582,0.00004327549],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.6523439,0.3228795,0.01199024,0.001989704,0.0004338497,0.0002138902,0.0004184944,0.0001957221,0.00953465],"genre_scores_gemma":[0.9163289,0.06964563,0.009238204,0.0004176582,0.0002012137,0.0001478101,0.0004917212,0.00001757342,0.003511302],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001412016,"threshold_uncertainty_score":0.004723608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03544263733315725,"score_gpt":0.3555745512982935,"score_spread":0.3201319139651362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}