{"id":"W2083823963","doi":"10.1155/2011/175364","title":"Intercellular Interactomics of Human Brain Endothelial Cells and Th17 Lymphocytes: A Novel Strategy for Identifying Therapeutic Targets of CNS Inflammation","year":2011,"lang":"en","type":"article","venue":"Cardiovascular Psychiatry and Neurology","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"Université de Montréal","keywords":"Neuroinflammation; Neuroscience; Homing (biology); Inflammation; Multiple sclerosis; Pathogenesis; Endothelium; Intracellular; Blood–brain barrier; Infiltration (HVAC); Cell biology; Medicine; Immunology; Biology; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002863783,0.0002677676,0.0003102429,0.0003556396,0.0002559237,0.0004697339,0.0001792719,0.0002916855,0.000986807],"category_scores_gemma":[0.0002558898,0.0001310321,0.0002251524,0.0002108352,0.0001665217,0.0002900214,0.0002537961,0.0005046745,0.0004123851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00017241,"about_ca_system_score_gemma":0.0001888025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002910596,"about_ca_topic_score_gemma":0.0007085405,"domain_scores_codex":[0.999866,0.00004058103,0.000008023424,0.00002987815,0.00003631663,0.00001911565],"domain_scores_gemma":[0.9999363,0.00001768055,0.0000139569,0.00000965374,0.00001367863,0.000008660368],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000466179,0.00001495795,0.0004014296,0.00003054671,0.000008340119,0.0000288189,0.0000163864,0.00006226385,0.9954388,0.0001281799,0.0000366376,0.003787091],"study_design_scores_gemma":[0.000009796814,0.0001423159,0.005466429,0.00000852508,0.00004074713,0.0002783987,0.00005725163,0.002395025,0.9875739,0.0003124556,0.003707676,0.000007470564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9148896,0.006501557,0.07445901,0.0005119675,0.00006227524,0.0001310174,0.0007536495,0.0001439803,0.002547009],"genre_scores_gemma":[0.929908,0.004162604,0.06164517,0.0002576938,0.00004889141,0.0001761843,0.001226855,0.00006241509,0.002512246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000986807,"threshold_uncertainty_score":0.003301203,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07017622677227156,"score_gpt":0.2744118187036332,"score_spread":0.2042355919313617,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}