{"id":"W2083826556","doi":"10.1016/j.pep.2011.06.021","title":"Improvement of the expression and purification of Mycobacterium tuberculosis arylamine N-acetyltransferase (TBNAT) a potential target for novel anti-tubercular agents","year":2011,"lang":"en","type":"article","venue":"Protein Expression and Purification","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Medical Research Council; University of Jordan; University of British Columbia","keywords":"Mycobacterium tuberculosis; Acetyltransferase; Tuberculosis; Microbiology; Biology; Virology; Chemistry; Medicine; Biochemistry; Acetylation; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002417305,0.0001561868,0.0001612781,0.00004333753,0.0001003049,0.00001278805,0.0001810109,0.0001924791,0.00001683772],"category_scores_gemma":[0.00007122911,0.0001128524,0.00009371258,0.00007432172,0.0001501126,0.00001328437,0.0001186652,0.00008298092,2.285914e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005676938,"about_ca_system_score_gemma":0.00002969497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002346022,"about_ca_topic_score_gemma":4.995282e-7,"domain_scores_codex":[0.9988387,0.0000568329,0.0003288267,0.0003961839,0.000204976,0.0001744635],"domain_scores_gemma":[0.9991549,0.000005427053,0.0001676145,0.0004060738,0.0001811182,0.0000848401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002776192,0.0002769153,0.0002116886,0.0002845517,0.00002324094,1.005957e-7,0.0001084096,0.00000335046,0.9964275,0.000061997,0.00005317805,0.002271443],"study_design_scores_gemma":[0.0009159606,0.0002580749,0.003117635,0.000105755,0.00002344659,0.000002600947,0.00004933757,0.0001936365,0.9940575,0.0001129718,0.0010324,0.0001306243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832415,0.0007040615,0.0143586,0.000176972,0.00004277765,0.001338966,0.00008863604,0.000005996128,0.00004247937],"genre_scores_gemma":[0.9950444,0.0003001845,0.004049587,0.00002911515,0.00003890741,0.0002985023,0.0001667038,0.00001921365,0.00005336948],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01180291,"threshold_uncertainty_score":0.4601989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01680284726874397,"score_gpt":0.2442704578278344,"score_spread":0.2274676105590904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}