{"id":"W2083843706","doi":"10.1110/ps.50901","title":"The HoxB1 hexapeptide is a prefolded domain: Implications for the Pbx1/Hox interaction","year":2001,"lang":"en","type":"article","venue":"Protein Science","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Hox gene; Homeobox; Peptide; DNA; Consensus sequence; Fusion protein; Chemistry; Biology; Gene; Binding site; Cell biology; Peptide sequence; Biochemistry; Transcription factor; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004737541,0.00007660389,0.00004262492,0.00001478904,0.0008646448,0.0001433942,0.0005982861,0.00003291765,0.000003777054],"category_scores_gemma":[0.0001144262,0.0000450306,0.00005338199,0.000166916,0.0002820819,0.000007560695,0.0001368031,0.00004892681,0.000005597145],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002721852,"about_ca_system_score_gemma":0.000110568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001496636,"about_ca_topic_score_gemma":0.00005361051,"domain_scores_codex":[0.9992686,0.00001300286,0.0001314205,0.0002583266,0.00009505851,0.0002335966],"domain_scores_gemma":[0.9992051,0.00002704446,0.00008617598,0.000506065,0.0001337198,0.00004188158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002078997,0.00001580146,0.000233889,0.000002725111,0.000008294347,4.239595e-8,0.0000685345,0.0000367658,0.9818895,0.002651741,0.0004264764,0.01464537],"study_design_scores_gemma":[0.000630159,0.0003769286,0.01817484,0.00002257917,0.00002124813,0.00006887217,0.0008734799,0.007432292,0.368416,0.0215388,0.5820504,0.0003943832],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9601738,0.0002984801,0.02868641,0.008385384,0.0001281508,0.001005353,0.00001377115,0.000009820465,0.001298823],"genre_scores_gemma":[0.9954466,0.0001423574,0.002614445,0.0002840532,0.0001032485,0.000439987,0.000005148365,0.000008127096,0.0009559812],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6134736,"threshold_uncertainty_score":0.6650236,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01486425455780543,"score_gpt":0.2842441737011629,"score_spread":0.2693799191433575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}