{"id":"W2083858958","doi":"10.1021/bi000760m","title":"Cytochrome <i>c</i> Peroxidase−Cytochrome <i>c</i> Complex:  Locating the Second Binding Domain on Cytochrome <i>c</i> Peroxidase with Site-Directed Mutagenesis","year":2000,"lang":"en","type":"article","venue":"Biochemistry","topic":"Porphyrin and Phthalocyanine Chemistry","field":"Materials Science","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Heart, Lung, and Blood Institute; Northwestern University","keywords":"Cytochrome c peroxidase; Peroxidase; Cytochrome c; Chemistry; Cytochrome c oxidase; Cytochrome; Coenzyme Q – cytochrome c reductase; Cytochrome P450 reductase; Cytochrome C1; Site-directed mutagenesis; Cytochrome b; Stereochemistry; Biochemistry; Enzyme; Mitochondrion; Gene; Mutant; Mitochondrial DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003656819,0.0004531047,0.0003369613,0.0001398095,0.0002143988,0.0003695021,0.0006073574,0.0005415425,0.0006807555],"category_scores_gemma":[0.0003330742,0.0002534469,0.00030183,0.0001515853,0.0003771912,0.0001618582,0.0003365315,0.0008289685,0.0002382237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008237758,"about_ca_system_score_gemma":0.000327988,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002174455,"about_ca_topic_score_gemma":0.002261325,"domain_scores_codex":[0.9996057,0.00008265646,0.00003837378,0.00009536584,0.0001168272,0.00006112017],"domain_scores_gemma":[0.9997744,0.00005540371,0.00006556923,0.00003044943,0.00003134794,0.00004285737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007019258,0.00003024585,0.0002689397,0.00002261849,0.000007016678,0.00004017565,0.00002109574,0.0001756607,0.9988337,0.0001024816,0.00002995949,0.0003978396],"study_design_scores_gemma":[0.00002863345,0.0001251438,0.002901755,0.000007093042,0.0000189381,0.0002802028,0.0000271067,0.002195514,0.9933935,0.00002351815,0.000990074,0.000008522648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955252,0.0001316715,0.003504562,0.00008282412,0.0000170831,0.0000670289,0.0001314013,0.00003771279,0.0005024551],"genre_scores_gemma":[0.9942086,0.0001413108,0.004392556,0.00006969732,0.000004268021,0.00004296709,0.0002912745,0.000034697,0.000814617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002174455,"threshold_uncertainty_score":0.005976975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01070573000828936,"score_gpt":0.2188892222555353,"score_spread":0.2081834922472459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}