{"id":"W2083869690","doi":"10.1002/iub.1146","title":"Cysteine‐capped gold nanoparticles suppress aggregation of proteins exposed to heat stress","year":2013,"lang":"en","type":"article","venue":"IUBMB Life","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Tellabs (Canada)","funders":"University of Zululand; National Research Foundation; Alexander von Humboldt-Stiftung","keywords":"Colloidal gold; Chemistry; Nanoparticle; Heat shock protein; Sodium borohydride; Bovine serum albumin; Reducing agent; Chaperone (clinical); Protein aggregation; Biophysics; Biomolecule; Dynamic light scattering; Cysteine; Biochemistry; Nanotechnology; Materials science; Organic chemistry; Enzyme; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001330177,0.0003141311,0.0002312554,0.0001677421,0.0001136829,0.0001501526,0.0001888344,0.0004555254,0.0003232774],"category_scores_gemma":[0.0002022189,0.0001466041,0.0001743964,0.00008770023,0.0002323115,0.000116132,0.0001483515,0.000224154,0.0001202995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002040492,"about_ca_system_score_gemma":0.0001203424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004569505,"about_ca_topic_score_gemma":0.0007201696,"domain_scores_codex":[0.9998938,0.00001881624,0.00000854261,0.00002394573,0.00003375238,0.00002115252],"domain_scores_gemma":[0.9999112,0.00001771082,0.0000183708,0.00001152836,0.00002614687,0.00001504413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001334438,0.000003946252,0.00001681566,0.00001142744,0.000001580177,0.0000117037,0.000005820648,0.00002598785,0.9995073,0.00002053148,0.00001072381,0.0003708035],"study_design_scores_gemma":[0.000002757962,0.00005626277,0.0003961629,0.000001484725,0.000003655327,0.00003609381,0.000004436963,0.0003195789,0.9988108,0.00001397823,0.0003533575,0.000001472484],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928935,0.001204393,0.004809116,0.00007411923,0.00004702717,0.00001920843,0.00003611989,0.00007707356,0.0008394105],"genre_scores_gemma":[0.991634,0.0005125188,0.005520124,0.00008072035,0.00001019682,0.00001948099,0.00009113726,0.00001696379,0.002114824],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004569505,"threshold_uncertainty_score":0.00148052,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01713260940223313,"score_gpt":0.2683917421231492,"score_spread":0.251259132720916,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}