{"id":"W2083893845","doi":"10.1002/1098-2396(20000901)37:3<171::aid-syn1>3.0.co;2-r","title":"Dopamine transporter function assessed by antisense knockdown in the rat: Protection from dopamine neurotoxicity","year":2000,"lang":"en","type":"article","venue":"Synapse","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Dopamine transporter; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic; Substantia nigra; Pars compacta; MPTP; Neurotoxin; Pharmacology; Amphetamine; Neurotoxicity; Chemistry; Biology; Internal medicine; Endocrinology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002183538,0.000825547,0.0006162805,0.0005203736,0.0003176157,0.0004319682,0.0003880071,0.0006657984,0.00132355],"category_scores_gemma":[0.0001753607,0.0003696221,0.0004989276,0.0002642013,0.0004659012,0.0004094978,0.0001846771,0.001254675,0.000574753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005359011,"about_ca_system_score_gemma":0.0005350148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003727525,"about_ca_topic_score_gemma":0.007031228,"domain_scores_codex":[0.9998035,0.00001580588,0.00001964277,0.00006389972,0.00004171777,0.00005548327],"domain_scores_gemma":[0.9997875,0.00001968604,0.00007873853,0.0000216201,0.00003831865,0.0000540937],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001351334,0.00005622015,0.0000712118,0.00001882482,0.000007343451,0.00003054684,0.00001426152,0.00003798325,0.9987271,0.00005957572,0.00004421397,0.0007975058],"study_design_scores_gemma":[0.00004908561,0.002016185,0.003056186,0.000006547452,0.0000875186,0.0002192726,0.00004646078,0.0008105058,0.9920374,0.00007203555,0.001584639,0.00001415029],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889128,0.001951308,0.005748435,0.0002895357,0.000114446,0.00007352815,0.001162399,0.0003565425,0.001391077],"genre_scores_gemma":[0.9775707,0.004614601,0.007225762,0.0001624883,0.00004587149,0.0002293743,0.00185448,0.0001609127,0.008135799],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003727525,"threshold_uncertainty_score":0.007411659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01371186157082531,"score_gpt":0.2359176360997887,"score_spread":0.2222057745289635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}