{"id":"W2083962744","doi":"10.1002/eji.200636938","title":"Non‐myeloablative mixed chimerism approaches and tolerance, a split decision","year":2007,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale","keywords":"Chimera (genetics); Immune tolerance; Clonal deletion; Biology; Immunology; Bone marrow; Antigen; CD8; Haematopoiesis; Transplantation Chimera; Mixed lymphocyte reaction; Immune system; T cell; Stem cell; Hematopoietic cell; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002429712,0.0001453764,0.0004089065,0.0003513356,0.0000705977,0.00001914187,0.0001810178,0.0000503988,0.0003667115],"category_scores_gemma":[0.0001668983,0.0001109841,0.0001173673,0.0002122772,0.0002810057,0.00008425709,0.0001010105,0.0006969782,0.00005281543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005285741,"about_ca_system_score_gemma":0.00006054112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002389466,"about_ca_topic_score_gemma":0.000001119457,"domain_scores_codex":[0.9984682,0.0002254938,0.0005641627,0.0001687656,0.0002554084,0.0003179686],"domain_scores_gemma":[0.9989836,0.0002079684,0.0002535702,0.0002344812,0.0001760783,0.0001442549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.005479414,0.0001496837,0.002868903,0.00001445767,0.0003558911,0.001713161,0.001589048,0.000004403416,0.2529718,0.0000763577,0.0004437341,0.7343332],"study_design_scores_gemma":[0.00777399,0.003781882,0.8884302,0.0002617378,0.00007409069,0.007103823,0.001205648,0.0000637413,0.02300007,0.0001212371,0.06799058,0.0001930346],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9636555,0.003294716,0.00451056,0.0003398991,0.0003023738,0.000151007,6.459093e-7,0.000009866104,0.02773547],"genre_scores_gemma":[0.9897004,0.0006188828,0.007161601,0.0001237393,0.0003706927,3.622762e-7,0.00000141079,0.0000404388,0.001982491],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8855613,"threshold_uncertainty_score":0.4525802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0361690223443372,"score_gpt":0.2871695163606968,"score_spread":0.2510004940163596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}