{"id":"W2083966880","doi":"10.1111/joim.12239","title":"Role of alpha‐1 antitrypsin in human health and disease","year":2014,"lang":"en","type":"review","venue":"Journal of Internal Medicine","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":249,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Alpha 1-antitrypsin deficiency; Context (archaeology); Cirrhosis; Disease; Immunology; Genotype; Panniculitis; Vasculitis; Internal medicine; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005966458,0.0001884152,0.001151719,0.0002072137,0.00001455721,0.0000041661,0.0002232067,0.0001111925,0.00001570395],"category_scores_gemma":[0.0003249961,0.0001243444,0.0001926083,0.00005309547,0.00007505128,0.000003384066,0.00007134112,0.0002791021,5.022849e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002504324,"about_ca_system_score_gemma":0.0002869087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000332367,"about_ca_topic_score_gemma":0.000005729539,"domain_scores_codex":[0.9983295,0.0001504587,0.001036386,0.000149389,0.0001975164,0.0001367378],"domain_scores_gemma":[0.9981919,0.00001504348,0.001205951,0.0001654777,0.00007927346,0.0003423517],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003626483,0.000280994,0.000349964,0.01863536,0.000454446,0.0001384802,0.000133563,4.061657e-7,0.02924933,0.000551917,0.01578199,0.9340609],"study_design_scores_gemma":[0.0008200954,0.00284397,0.00001765109,0.04884801,0.0001412951,0.0002611647,0.00003633538,0.000001728721,0.0009067285,0.0004928738,0.9454917,0.0001384062],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001684027,0.9975694,0.0001642354,0.0001022009,0.0001990667,0.0001402279,0.000007088765,7.852968e-7,0.0001329732],"genre_scores_gemma":[0.008746727,0.9896343,0.00007340903,0.000298755,0.001135909,0.000002363653,0.00001605009,0.00002048959,0.00007200881],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9339225,"threshold_uncertainty_score":0.5070618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01605340756088878,"score_gpt":0.344063434485247,"score_spread":0.3280100269243582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}