{"id":"W2083974470","doi":"10.1016/s0960-894x(00)00400-5","title":"Synthesis and 5-Hydroxytryptamine (5-HT) activity of 2,3,4,4a-Tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-Hexahydro-1H-pyrazino[1,2-a]quinoxalines","year":2000,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Chemistry; Stereochemistry; Chemical synthesis; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001690287,0.0002443609,0.000238835,0.0002485633,0.0001787571,0.0001658337,0.0003487537,0.0002429872,0.002066962],"category_scores_gemma":[0.0002045003,0.0001931725,0.0002467376,0.000134859,0.0001905566,0.0002854153,0.0001478944,0.0003016666,0.0005262789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001459598,"about_ca_system_score_gemma":0.0001903627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003886344,"about_ca_topic_score_gemma":0.0005923435,"domain_scores_codex":[0.9999042,0.00002306432,0.00001331185,0.00001414116,0.00002123385,0.0000240921],"domain_scores_gemma":[0.9999039,0.00002112125,0.00002062126,0.00001243901,0.00001494958,0.00002694353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005510749,0.00009313448,0.0001015701,0.0001573256,0.00001785685,0.0002573105,0.00005082512,0.0007080513,0.9915005,0.0006083272,0.0001355295,0.005818543],"study_design_scores_gemma":[0.0001677846,0.003325729,0.001747693,0.00001311859,0.00003073489,0.0004780334,0.0000266585,0.000982049,0.9889849,0.0001284473,0.004094034,0.00002069566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9808035,0.008041609,0.004317459,0.0001756942,0.0001091712,0.0001625625,0.0007957261,0.00008529376,0.005508817],"genre_scores_gemma":[0.9889586,0.003269714,0.003003651,0.00005499917,0.00005184784,0.00006700158,0.0009362007,0.00001138153,0.003646578],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002066962,"threshold_uncertainty_score":0.006914675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01364525367809682,"score_gpt":0.2265792113874799,"score_spread":0.2129339577093831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}