{"id":"W2083974470","doi":"10.1016/s0960-894x(00)00400-5","title":"Synthesis and 5-Hydroxytryptamine (5-HT) activity of 2,3,4,4a-Tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-Hexahydro-1H-pyrazino[1,2-a]quinoxalines","year":2000,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Chemistry; Stereochemistry; Chemical synthesis; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008015022,0.0009418754,0.001288577,0.0001036676,0.0002999779,0.00008699909,0.0006318523,0.0007585638,0.008839074],"category_scores_gemma":[0.0009981317,0.0008006322,0.0002712597,0.0004053597,0.001393534,0.0002590707,0.0002004312,0.0006708814,0.00004338683],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001611091,"about_ca_system_score_gemma":0.0001107448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001920054,"about_ca_topic_score_gemma":0.000008891516,"domain_scores_codex":[0.9953267,0.0001167799,0.001125108,0.001427421,0.001055683,0.0009483068],"domain_scores_gemma":[0.9970596,0.000762481,0.0005728698,0.0009194344,0.0001342251,0.0005513779],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003135174,0.0002737829,0.004525199,0.0008314783,0.0001522741,0.00005512479,0.0001681479,0.000006166371,0.9541516,0.000005107273,0.0006810494,0.03883652],"study_design_scores_gemma":[0.001329372,0.00007405398,0.01057525,0.0005346811,0.0004790659,0.000287844,0.0002499081,0.0005956581,0.9825374,0.00006670104,0.002361891,0.0009081051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914836,0.002130518,0.00001960459,0.0036453,0.0001112407,0.0002153357,0.0001241472,0.0002145413,0.002055772],"genre_scores_gemma":[0.9960763,0.001504545,0.0001865823,0.0006199434,0.001068623,0.00005729356,0.00007244971,0.00009443155,0.0003198347],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03792842,"threshold_uncertainty_score":0.9994445,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01364525367809682,"score_gpt":0.2265792113874799,"score_spread":0.2129339577093831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}