{"id":"W2084002557","doi":"10.1038/sj.mp.4002098","title":"Prominent synaptic and metabolic abnormalities revealed by proteomic analysis of the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder","year":2007,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":229,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Wellcome Trust","keywords":"Bipolar disorder; Schizophrenia (object-oriented programming); Dorsolateral prefrontal cortex; Prefrontal cortex; Psychosis; Septin; Neuroscience; Psychology; Psychiatry; Biology; Genetics; Cognition","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001191227,0.0001530242,0.0002459196,0.0001094462,0.00005607128,0.00001416505,0.0001440381,0.00008188827,0.00002955443],"category_scores_gemma":[0.000006704483,0.0001131376,0.00008062661,0.000315652,0.0001107639,0.00003989141,0.00008009813,0.0001650422,2.920142e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001407262,"about_ca_system_score_gemma":0.00001940734,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001726058,"about_ca_topic_score_gemma":0.0002041024,"domain_scores_codex":[0.9991178,0.00001761017,0.0003079464,0.0002660335,0.0001025556,0.0001880476],"domain_scores_gemma":[0.9994389,0.000007981401,0.0001522062,0.0003363878,0.00001435276,0.00005017922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00008115583,0.00009732363,0.3048388,0.00009852019,0.0003509738,0.000001173226,0.0001060551,0.000009638243,0.6902592,0.003281974,0.0000159001,0.0008593134],"study_design_scores_gemma":[0.003109623,0.00008232589,0.634237,0.0002284782,0.001632238,0.00004571872,0.0003329844,0.002365995,0.3460081,0.007874296,0.003066804,0.001016478],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906329,0.004368609,0.004159463,0.0001844627,0.00001067162,0.0003894352,0.00003822405,0.00003038851,0.0001858271],"genre_scores_gemma":[0.984519,0.0001094488,0.01495595,0.00005064438,0.000009170888,0.00009810885,0.00001539119,0.00002815755,0.0002141315],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3442511,"threshold_uncertainty_score":0.4613618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002535776654822803,"score_gpt":0.2229976967022625,"score_spread":0.2204619200474397,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}