{"id":"W2084054430","doi":"10.1002/1521-4141(200104)31:4<1211::aid-immu1211>3.0.co;2-r","title":"Human T cell subset commitment determined by the intrinsic property of antigen: the proteolytic activity of the major mite allergen Der p 1 conditions T cells to produce more IL-4 and less IFN-γ","year":2001,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Allergic Rhinitis and Sensitization","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Biology; Immunoglobulin E; IL-2 receptor; Secretion; Immunology; T cell; CD8; Cytokine; Allergen; Antigen; Antigen-presenting cell; Cell biology; Antibody; Immune system; Allergy; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001258689,0.0001911289,0.0001533186,0.000112514,0.0001167661,0.0002836704,0.0000742901,0.0001874786,0.002900119],"category_scores_gemma":[0.0001767391,0.00008347279,0.0001280199,0.0001063607,0.0001089536,0.0001475042,0.0001372948,0.0002602666,0.0006484218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001003923,"about_ca_system_score_gemma":0.00008914432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001103706,"about_ca_topic_score_gemma":0.0002014539,"domain_scores_codex":[0.9999028,0.00002057799,0.000008353922,0.0000237241,0.00001336229,0.00003114028],"domain_scores_gemma":[0.9999439,0.00001323381,0.000009635251,0.00001511037,0.000007699502,0.00001045422],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009859075,0.00009886238,0.0046006,0.00005397059,0.00001058745,0.0003157486,0.00006792931,0.00007815671,0.984659,0.0001223272,0.0001434026,0.008863641],"study_design_scores_gemma":[0.0002097341,0.004154757,0.0948038,0.00002450631,0.000118398,0.007852919,0.000244156,0.0009959607,0.8782445,0.0004175489,0.01291732,0.00001640006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968131,0.001046102,0.0005204806,0.00003877818,0.00001181524,0.00002168295,0.00008554242,0.00001449575,0.001448024],"genre_scores_gemma":[0.9970294,0.0006227034,0.0004764483,0.00005620481,0.00002168491,0.00002609826,0.0003239513,0.000006759436,0.001436686],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002900119,"threshold_uncertainty_score":0.009701908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02003455701548669,"score_gpt":0.2447943680300091,"score_spread":0.2247598110145224,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}