{"id":"W2084056048","doi":"10.1038/onc.2008.210","title":"Leukemogenic properties of NUP98-PMX1 are linked to NUP98 and homeodomain sequence functions but not to binding properties of PMX1 to serum response factor","year":2008,"lang":"en","type":"article","venue":"Oncogene","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Canadian Institutes of Health Research; Terry Fox Foundation","keywords":"Biology; Homeobox; Cancer research; Haematopoiesis; Myeloid; Myeloid leukemia; Hox gene; Leukemia; Myeloproliferative Disorders; Progenitor cell; Stem cell; Carcinogenesis; Genetics; Molecular biology; Cell biology; Gene; Transcription factor; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002120238,0.0003175851,0.0001647984,0.0002465523,0.0002740928,0.0003171143,0.0002634475,0.0002416605,0.002103842],"category_scores_gemma":[0.0002327456,0.000167457,0.0002010201,0.0001538869,0.0003061371,0.0002670726,0.000362601,0.0004958516,0.000487361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002082958,"about_ca_system_score_gemma":0.00008900824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002303852,"about_ca_topic_score_gemma":0.0002860888,"domain_scores_codex":[0.9998492,0.00003537972,0.00001318039,0.00002640659,0.00004139971,0.00003437401],"domain_scores_gemma":[0.9997545,0.00006602606,0.00005754547,0.00004719817,0.00001420229,0.00006048407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001237341,0.000021949,0.0003371923,0.00001198041,0.000003100864,0.00003620318,0.00001040216,0.00002632368,0.9985635,0.0001408225,0.00002120932,0.0007037583],"study_design_scores_gemma":[0.00001357456,0.0001326599,0.01058648,0.000002272124,0.000007287673,0.0008360695,0.00002027868,0.0006459292,0.9862278,0.00007237649,0.001452843,0.000002499835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974446,0.0005176882,0.001157283,0.00004150614,0.000008092968,0.000009237314,0.0001384542,0.00002916776,0.0006539776],"genre_scores_gemma":[0.9973007,0.0001406807,0.0006487108,0.00001556784,0.00000451368,0.00001286877,0.00052158,0.00001377108,0.001341602],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002103842,"threshold_uncertainty_score":0.007038057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1177583616893573,"score_gpt":0.3106922652476507,"score_spread":0.1929339035582934,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}