{"id":"W2084056048","doi":"10.1038/onc.2008.210","title":"Leukemogenic properties of NUP98-PMX1 are linked to NUP98 and homeodomain sequence functions but not to binding properties of PMX1 to serum response factor","year":2008,"lang":"en","type":"article","venue":"Oncogene","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Canadian Institutes of Health Research; Terry Fox Foundation","keywords":"Biology; Homeobox; Cancer research; Haematopoiesis; Myeloid; Myeloid leukemia; Hox gene; Leukemia; Myeloproliferative Disorders; Progenitor cell; Stem cell; Carcinogenesis; Genetics; Molecular biology; Cell biology; Gene; Transcription factor; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006528142,0.0003590374,0.0008331229,0.0007913747,0.0002468056,0.00002245347,0.0003371054,0.000195793,0.00008571983],"category_scores_gemma":[0.001833659,0.0002818784,0.0001395279,0.001075843,0.0002981528,0.0001499093,0.0003973531,0.0003266655,0.0002671357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009699883,"about_ca_system_score_gemma":0.001442535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003836053,"about_ca_topic_score_gemma":0.00008241391,"domain_scores_codex":[0.9968333,0.0002541193,0.0006919514,0.0006489712,0.0008890338,0.0006826064],"domain_scores_gemma":[0.997612,0.000121267,0.0001565113,0.0007944107,0.0006076755,0.0007081359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008029182,0.0001216129,0.004486112,0.0003102747,0.0001363852,0.000125031,0.004576246,0.00007445702,0.9794745,0.000002122189,0.001115732,0.001548387],"study_design_scores_gemma":[0.001631128,0.001632948,0.03262503,0.0008771219,0.00006585234,0.0002969626,0.002532948,0.00006717832,0.9564791,8.574932e-7,0.003444314,0.0003466101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922751,0.0004530667,0.0001192464,0.00466705,0.0001176778,0.001902996,0.0003064768,0.00008624425,0.00007220519],"genre_scores_gemma":[0.9842021,0.0001142346,0.002094426,0.0007642419,0.0001533579,0.0001581175,0.000006503609,0.00008396158,0.01242305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02813892,"threshold_uncertainty_score":0.9999633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1177583616893573,"score_gpt":0.3106922652476507,"score_spread":0.1929339035582934,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}