{"id":"W2084072781","doi":"10.1016/j.mce.2005.09.013","title":"The role of cyclic AMP response element binding protein in transactivation of scavenger receptor class B type I promoter in transfected cells and in primary cultures of rat theca-interstitial cells","year":2005,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"University of British Columbia; University of South Florida; H. Lee Moffitt Cancer Center and Research Institute","keywords":"Transactivation; CREB; Transfection; Molecular biology; CREB1; Biology; Response element; Cyclic AMP Response Element-Binding Protein; Forskolin; Reporter gene; Protein kinase A; HEK 293 cells; Chemistry; Receptor; Cell culture; Cell biology; Phosphorylation; Transcription factor; Promoter; Gene expression; Gene; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004993663,0.0003522552,0.0004286191,0.0006072214,0.0005823375,0.0007493076,0.0004418976,0.0004863059,0.002237825],"category_scores_gemma":[0.000419826,0.0005215667,0.0006661679,0.0003559081,0.0006022563,0.0005119282,0.0002928092,0.001126849,0.0008800878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007825355,"about_ca_system_score_gemma":0.0006201045,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004141442,"about_ca_topic_score_gemma":0.005461201,"domain_scores_codex":[0.9996243,0.00009475666,0.00003218287,0.00007541946,0.00007296352,0.0001003873],"domain_scores_gemma":[0.9994401,0.0002318351,0.00003581145,0.0001166542,0.00006952626,0.0001059113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007515284,0.00001186325,0.00006457558,0.00001773342,0.0000030782,0.00002766367,0.00003023031,0.00001294793,0.9993101,0.000154619,0.00001564906,0.0002763215],"study_design_scores_gemma":[0.00003274402,0.0001337929,0.006244252,0.00001246714,0.0000305759,0.0002888235,0.00009154485,0.001060358,0.9896359,0.0001498204,0.002311351,0.000008415008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.978815,0.007885223,0.0080782,0.0004615244,0.0001345972,0.00004509525,0.000999318,0.00017289,0.003408048],"genre_scores_gemma":[0.9790445,0.002140747,0.005399008,0.0001467312,0.00007061684,0.00009126122,0.002472432,0.0001006488,0.01053406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004141442,"threshold_uncertainty_score":0.00823468,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00322952108276752,"score_gpt":0.2066379501973854,"score_spread":0.2034084291146179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}