{"id":"W2084082252","doi":"10.1016/j.ntt.2012.08.005","title":"Alterations of neocortical development and maturation in autism: Insight from valproic acid exposure and animal models of autism","year":2012,"lang":"en","type":"review","venue":"Neurotoxicology and Teratology","topic":"Autism Spectrum Disorder Research","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Neocortex; Valproic Acid; Neuroscience; Autism; Neuropathology; White matter; Autism spectrum disorder; Brain development; Neurodevelopmental disorder; Grey matter; Pathological; Psychology; Developmental disorder; Biology; Developmental psychology; Medicine; Epilepsy; Pathology; Disease; Magnetic resonance imaging","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001544538,0.000340108,0.001325024,0.0004325006,0.0001163227,0.00002603036,0.0001840965,0.0006195793,0.0000391234],"category_scores_gemma":[0.0001027393,0.0003020612,0.00004854307,0.0002652338,0.0006302756,0.0002404849,0.0003336469,0.0007094294,0.000003139688],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002312189,"about_ca_system_score_gemma":0.000253564,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001175657,"about_ca_topic_score_gemma":0.00007209805,"domain_scores_codex":[0.9968778,0.0009468812,0.0008922091,0.000711038,0.0001544053,0.00041762],"domain_scores_gemma":[0.9986798,0.0006318812,0.0003147413,0.0002422616,0.00000825703,0.0001230664],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005065621,0.001099527,0.002527141,0.007547695,0.0001206511,0.0004435698,0.004372038,0.000002023526,0.0262819,0.4939993,0.00001311406,0.4630865],"study_design_scores_gemma":[0.02039348,0.01424471,0.2450169,0.01071537,0.003289188,0.01774983,0.0001441688,0.00934392,0.1160209,0.159306,0.3954512,0.008324392],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.2852674,0.7119654,0.0001427558,0.000540612,0.0001434642,0.001728393,0.00005083249,0.00002344637,0.0001376716],"genre_scores_gemma":[0.6201431,0.3791963,0.0002968586,0.00006389243,0.00000903047,0.0002446571,0.00001564516,0.00002195238,0.000008558455],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.454762,"threshold_uncertainty_score":0.9999431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08678122414175281,"score_gpt":0.3340965123925062,"score_spread":0.2473152882507534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}