{"id":"W2084130169","doi":"10.1371/journal.pone.0039244","title":"Up-Regulation of Annexin-A1 and Lipoxin A4 in Individuals with Ulcerative Colitis May Promote Mucosal Homeostasis","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"ca_institutions":"Population Health Research Institute; McMaster University; University of Calgary; SickKids Foundation; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Crohn's and Colitis Foundation of Canada; Crohn's and Colitis Foundation; University of Calgary","keywords":"Annexin A1; Lamina propria; Ulcerative colitis; Inflammation; Receptor; Colitis; Downregulation and upregulation; Medicine; Immunology; Lipoxin; Homeostasis; Immunohistochemistry; Pathology; Internal medicine; Annexin; Endocrinology; Biology; Epithelium; Flow cytometry; Disease; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001807885,0.0001177205,0.0001809649,0.0000600662,0.00003407149,0.00001292347,0.00005824567,0.0001039529,0.00003465867],"category_scores_gemma":[0.00003904082,0.0001034587,0.00001968237,0.0001034505,0.00008222443,0.00001378032,0.00005623901,0.00006259554,0.000002354079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001000345,"about_ca_system_score_gemma":0.00003485609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004319307,"about_ca_topic_score_gemma":0.0001045813,"domain_scores_codex":[0.9992199,0.00006195105,0.0001591153,0.0001890757,0.000150215,0.0002197499],"domain_scores_gemma":[0.9996027,0.000008337155,0.00008717344,0.0001596959,0.00006923106,0.00007280977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003263268,0.001475226,0.2615186,0.0001732348,0.0003260416,0.000001152824,0.001237713,0.000003246498,0.7276022,0.0005224943,0.00008673069,0.006726989],"study_design_scores_gemma":[0.0007334877,0.0005007861,0.3144599,0.00008932174,0.00003347491,0.000003033605,0.0001104988,0.00001625942,0.683529,0.00004316424,0.0003418218,0.0001392706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983819,0.0006049592,0.00004226757,0.0001378513,0.00001143952,0.0003839723,0.00007906812,0.000006523559,0.0003520691],"genre_scores_gemma":[0.9969449,0.00009921422,0.002339287,0.00004457913,0.000108371,0.00004834929,0.00009911878,0.00001749718,0.0002986665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05294123,"threshold_uncertainty_score":0.4218924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02206938651588234,"score_gpt":0.2352500090720099,"score_spread":0.2131806225561276,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}