{"id":"W2084132599","doi":"10.1161/01.res.0000216595.15868.55","title":"Shear Stress Regulates Forward and Reverse Planar Cell Polarity of Vascular Endothelium In Vivo and In Vitro","year":2006,"lang":"en","type":"article","venue":"Circulation Research","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":133,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Cell polarity; Endothelium; Cell biology; Endothelial stem cell; Polarity (international relations); Mechanosensitive channels; Biology; Cytoskeleton; Microtubule; Shear stress; Cytoplasm; Cell; In vitro; Materials science; Biochemistry; Endocrinology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005112228,0.00006878172,0.0001155011,0.0001370639,0.00003802712,0.00001445086,0.00005969273,0.0001215733,0.00001016629],"category_scores_gemma":[0.00002748742,0.00007045246,0.00003181676,0.0001410493,0.0001095077,0.000006341922,0.00004792628,0.00007854989,4.335644e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000200706,"about_ca_system_score_gemma":0.00003999472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001882377,"about_ca_topic_score_gemma":0.0003413791,"domain_scores_codex":[0.9991027,0.0001179428,0.0001684458,0.0002467396,0.0001723159,0.0001919152],"domain_scores_gemma":[0.9996664,0.00002624032,0.00003026807,0.0001698992,0.00007189501,0.00003531061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005994788,0.00003684479,0.2469341,0.00005890839,0.00000449122,0.00000227136,0.00002460767,0.0002745358,0.7523538,0.00003323148,0.00006323292,0.0001540606],"study_design_scores_gemma":[0.0006745991,0.00003186668,0.4083543,0.00002148672,0.000003474757,0.000002016083,0.0001002341,0.0006692663,0.5889317,0.0002492656,0.0008716593,0.00009007584],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961581,0.003152389,0.00006660324,0.00006201697,0.00001114962,0.0001752079,0.00004105033,0.000001797323,0.0003316876],"genre_scores_gemma":[0.9992495,0.0003628646,0.0001632275,0.00001210247,0.00004820466,0.00001067289,0.000042756,0.000009718553,0.0001009123],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1634221,"threshold_uncertainty_score":0.2872968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01829562220687123,"score_gpt":0.288273760709474,"score_spread":0.2699781385026027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}