{"id":"W2084156736","doi":"10.1016/j.febslet.2014.02.064","title":"Atrial fibrillation‐linked <i>GJA5</i>/connexin40 mutants impaired gap junctions via different mechanisms","year":2014,"lang":"en","type":"review","venue":"FEBS Letters","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Mutant; Gap junction; Germline; Mutation; Germline mutation; Pathogenesis; Somatic cell; Genetics; Atrial fibrillation; Cell biology; Biology; Connexin; Gene; Medicine; Internal medicine; Immunology; Intracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002488502,0.0007751377,0.001515661,0.0001814185,0.0002156543,0.00005953121,0.0004510772,0.0008746942,0.0001668869],"category_scores_gemma":[0.0001085593,0.0006289511,0.00164901,0.0001575486,0.0001232258,0.000004174986,0.0002623438,0.0003371603,0.0001660269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007706181,"about_ca_system_score_gemma":0.0001149334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002342799,"about_ca_topic_score_gemma":0.00004934526,"domain_scores_codex":[0.9968715,0.0004572471,0.0008273193,0.001024138,0.0001949757,0.0006248553],"domain_scores_gemma":[0.9981609,0.00009029642,0.0005169522,0.0009792492,0.00006191157,0.0001906791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001985495,0.00004966344,0.00002921985,0.002716509,0.001940509,0.00003078385,0.00003186364,0.00003408278,0.0266,0.0004788343,0.01902039,0.9488696],"study_design_scores_gemma":[0.0006298409,0.0002973953,0.00001847372,0.0004382367,0.0006488772,0.0001185969,0.000003496572,0.00002711073,0.0001097894,0.00008289497,0.9968692,0.0007561101],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002355569,0.9737748,0.01700566,0.0006456915,0.004279229,0.00139327,0.0002556032,0.000108536,0.0001816283],"genre_scores_gemma":[0.003343825,0.9846871,0.0003055363,0.001490739,0.006027197,0.00006855837,0.003342837,0.0001614384,0.0005727545],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9778488,"threshold_uncertainty_score":0.9996162,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0281652396383372,"score_gpt":0.2813227805139914,"score_spread":0.2531575408756542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}