{"id":"W2084186494","doi":"10.1021/nn2007496","title":"Effect of Gold Nanoparticle Aggregation on Cell Uptake and Toxicity","year":2011,"lang":"en","type":"article","venue":"ACS Nano","topic":"Nanoparticles: synthesis and applications","field":"Materials Science","cited_by":841,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"HeLa; Intracellular; Nanoparticle; Biophysics; Chemistry; Cell; Endocytosis; Toxicity; A549 cell; Colloidal gold; Dispersity; Nanotechnology; Nanotoxicology; Cell biology; Materials science; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003982911,0.00008354925,0.0001313481,0.00002656748,0.00005602026,0.00001614773,0.0001138878,0.00003696951,0.0001219692],"category_scores_gemma":[0.00005267988,0.00006463382,0.00002432185,0.0001092333,0.00007164158,0.00009290187,0.00003446608,0.00002377899,0.000183023],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009538943,"about_ca_system_score_gemma":0.000008403256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003502137,"about_ca_topic_score_gemma":0.000003238181,"domain_scores_codex":[0.999297,0.00007087639,0.0001801388,0.0001845438,0.0001167312,0.0001506652],"domain_scores_gemma":[0.9994615,0.0001199324,0.00009040908,0.0002481516,0.00002426004,0.00005572783],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004585015,0.00009570903,0.0007525517,0.00001897638,0.000001284416,4.201407e-7,0.0001639218,0.000001125921,0.9924003,0.0008977479,0.0001146696,0.005507419],"study_design_scores_gemma":[0.0002504144,0.0003779551,0.002464955,0.00001889217,0.00001670842,9.27897e-7,0.000009767063,0.00002180667,0.996387,0.0002120982,0.0001714746,0.00006800705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974939,0.00005613035,0.00001530534,0.000034179,0.00004625511,0.0001860795,0.000008570875,0.00003438772,0.002125196],"genre_scores_gemma":[0.9994282,0.000008387655,0.0003371572,0.00003684572,0.00001514843,0.00003348145,5.437293e-7,0.000008091918,0.0001322043],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005439412,"threshold_uncertainty_score":0.2635691,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01710964202786568,"score_gpt":0.2345387536635938,"score_spread":0.2174291116357281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}