{"id":"W2084242431","doi":"10.1002/ana.22065","title":"Reciprocal Th1 and Th17 regulation by mesenchymal stem cells: Implication for multiple sclerosis","year":2010,"lang":"en","type":"article","venue":"Annals of Neurology","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; McGill University; Jewish General Hospital; Montreal Neurological Institute and Hospital","funders":"National Cancer Institute; Canadian Institutes of Health Research; Chinese Academy of Agricultural Sciences","keywords":"Mesenchymal stem cell; Multiple sclerosis; Proinflammatory cytokine; Immune system; Immunology; Interleukin 17; Cytokine; Bone marrow; Medicine; Biology; Cancer research; Inflammation; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003840777,0.0002773878,0.0003078742,0.0002030162,0.0001285133,0.0002561041,0.00008183414,0.0002154488,0.001797319],"category_scores_gemma":[0.0001447931,0.00006656305,0.0001912325,0.0001582409,0.0002924633,0.0001463006,0.0001576484,0.0005681368,0.0002085327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001033312,"about_ca_system_score_gemma":0.0001717608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000245109,"about_ca_topic_score_gemma":0.0006053154,"domain_scores_codex":[0.9997969,0.00007287625,0.00002313498,0.0000231251,0.00005052985,0.00003348299],"domain_scores_gemma":[0.9998435,0.00005733683,0.00003129595,0.00001936906,0.00001522361,0.00003322321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006094959,0.0001265512,0.0008754124,0.0001595579,0.00001453313,0.00009489716,0.00003244189,0.00008413638,0.9893828,0.0001244935,0.00004958851,0.008445977],"study_design_scores_gemma":[0.00007945694,0.00270055,0.01122262,0.00002059232,0.00006218942,0.0003955636,0.00007360475,0.0003139342,0.9824986,0.0001028945,0.002525982,0.000004100394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926597,0.004666166,0.001113798,0.0001164218,0.00004308856,0.00004623199,0.0001833727,0.00002401714,0.001147103],"genre_scores_gemma":[0.9942941,0.001932408,0.002370205,0.0001133738,0.00004042283,0.00006043779,0.0001682753,0.00000938336,0.001011304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001797319,"threshold_uncertainty_score":0.006012619,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1445363533567513,"score_gpt":0.3526886018673003,"score_spread":0.2081522485105489,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}