{"id":"W2084253472","doi":"10.1038/nature07392","title":"DNA double-strand breaks activate a multi-functional genetic program in developing lymphocytes","year":2008,"lang":"en","type":"article","venue":"Nature","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":149,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Cancer Research","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health","keywords":"Biology; DNA repair; DNA damage; DNA; Gene; Cell biology; Genetics; Transcription (linguistics); Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002664896,0.000257267,0.0002072024,0.0004807663,0.0001644537,0.0005466622,0.0003502672,0.0003671878,0.001163422],"category_scores_gemma":[0.0002131032,0.0002646041,0.0002028505,0.000216547,0.0002185865,0.0003115521,0.0003379788,0.0006212451,0.0003965298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003361356,"about_ca_system_score_gemma":0.0001652305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001802984,"about_ca_topic_score_gemma":0.0003566817,"domain_scores_codex":[0.9998491,0.0000231919,0.0000129831,0.00002667485,0.00005098981,0.00003696926],"domain_scores_gemma":[0.9997079,0.0000808918,0.00006057234,0.00005267798,0.00004032741,0.00005773204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000569805,0.000007850529,0.00051211,0.00001772321,0.000002363421,0.00008380545,0.00001487988,0.00008456479,0.9968693,0.0005742239,0.00002024519,0.001756078],"study_design_scores_gemma":[0.00001828556,0.0001520139,0.01188985,0.000008368992,0.00001615475,0.0005228149,0.00006099716,0.0008394227,0.984228,0.0004059976,0.001853402,0.000004668096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886454,0.001565894,0.006806721,0.00008212181,0.00002260364,0.0000197362,0.0001338668,0.0001556341,0.002568],"genre_scores_gemma":[0.993274,0.0006784934,0.002330274,0.00003781853,0.0000139271,0.00001977154,0.0001994588,0.0000372129,0.003408964],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001163422,"threshold_uncertainty_score":0.003892064,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01654952196559014,"score_gpt":0.2640274201103098,"score_spread":0.2474778981447196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}