{"id":"W2084308670","doi":"10.1016/j.pathophys.2006.06.001","title":"The Na+/K+-ATPase as [K+]o sensor: Role in cardiovascular disease pathogenesis and augmented production of endogenous cardiotonic steroids","year":2006,"lang":"en","type":"article","venue":"Pathophysiology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Ouabain; Hypokalemia; Endogeny; Pathogenesis; Internal medicine; Endocrinology; Intracellular; Extracellular; ATPase; Medicine; Chemistry; Sodium; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001901356,0.0001334973,0.0002067552,0.00003843951,0.00009213373,0.000005113394,0.00007165292,0.00009506401,0.000001465015],"category_scores_gemma":[0.0000229613,0.0001074988,0.0001623783,0.00008270734,0.0001548489,0.000003484014,0.00003112013,0.00004499079,0.000002008427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001259559,"about_ca_system_score_gemma":0.00004507386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001251704,"about_ca_topic_score_gemma":0.00002294154,"domain_scores_codex":[0.9989518,0.000150599,0.0002257011,0.0003515599,0.0001126295,0.0002076903],"domain_scores_gemma":[0.9994273,0.00000840259,0.00006566922,0.0003914533,0.00006621072,0.00004093666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002579844,0.00004933434,0.003846412,0.00002801067,0.00006746783,0.00001295266,0.00002985476,0.003050887,0.9876486,0.00004082025,0.000008115569,0.004959548],"study_design_scores_gemma":[0.001442419,0.0004460843,0.2893615,0.00002720095,0.0002313311,0.00004607916,0.0003184056,0.0002838835,0.7014347,0.001767072,0.004212666,0.0004286041],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876573,0.01169801,0.00007907105,0.00004010558,0.0001712313,0.0002814249,0.00001786822,0.000007956311,0.0000470291],"genre_scores_gemma":[0.998281,0.00110512,0.00003039199,0.00001637212,0.0002069616,0.00005775873,0.0001831787,0.00001655797,0.0001026723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2862138,"threshold_uncertainty_score":0.4383675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005211262343511327,"score_gpt":0.1841682368416762,"score_spread":0.1789569744981649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}