{"id":"W2084339384","doi":"10.2174/157016208783884985","title":"Nef and TNFα are Coplayers that Favor HIV-1 Replication in Monocytic Cells and Primary Macrophages","year":2008,"lang":"en","type":"article","venue":"Current HIV Research","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"University of Leeds","keywords":"Replication (statistics); Tumor necrosis factor alpha; Virology; Human immunodeficiency virus (HIV); Primary cell; Cell biology; Biology; Chemistry; Immunology; Cell culture; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007246857,0.0001924816,0.0002984111,0.0004071965,0.0004397372,0.00004060757,0.0002248934,0.0001521316,0.0001453158],"category_scores_gemma":[0.0001416729,0.0001645767,0.00003992865,0.0002864412,0.0007980274,0.000128997,0.0003090866,0.0007959669,0.001833407],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000209629,"about_ca_system_score_gemma":0.0001763691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000972104,"about_ca_topic_score_gemma":0.00004724467,"domain_scores_codex":[0.9975712,0.0005462273,0.0002299631,0.0007040455,0.000174131,0.0007744341],"domain_scores_gemma":[0.9986959,0.0004340248,0.00005636643,0.00058162,0.000106684,0.0001254174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00114643,0.001355257,0.5605437,0.0006231728,0.0002012472,0.0002319091,0.00328153,0.000005550186,0.1583751,0.0001305886,0.1605795,0.113526],"study_design_scores_gemma":[0.007209133,0.0003920162,0.684389,0.0002806737,0.00002324153,0.0002879355,0.0007586922,0.00002530627,0.04450602,0.0001753761,0.2614694,0.0004832628],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9637582,0.03377949,0.00003408709,0.0006780731,0.0001045462,0.0007782319,0.0002401335,0.00003609069,0.0005911014],"genre_scores_gemma":[0.9765421,0.01742411,0.00006346011,0.00001635654,0.00002652,0.0001632208,0.0005460568,0.00002017643,0.005198017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1238453,"threshold_uncertainty_score":0.9989438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1319159985554597,"score_gpt":0.3641496392700644,"score_spread":0.2322336407146047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}