{"id":"W2084339384","doi":"10.2174/157016208783884985","title":"Nef and TNFα are Coplayers that Favor HIV-1 Replication in Monocytic Cells and Primary Macrophages","year":2008,"lang":"en","type":"article","venue":"Current HIV Research","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"University of Leeds","keywords":"Replication (statistics); Tumor necrosis factor alpha; Virology; Human immunodeficiency virus (HIV); Primary cell; Cell biology; Biology; Chemistry; Immunology; Cell culture; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009937318,0.0003370505,0.0002271742,0.0001649206,0.0002131579,0.0003147664,0.0001079183,0.0002626524,0.001307519],"category_scores_gemma":[0.0001082047,0.0001614171,0.0001607247,0.0001051911,0.0001976739,0.0002003311,0.000219468,0.0002734814,0.0006976626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000293308,"about_ca_system_score_gemma":0.0001476274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005365489,"about_ca_topic_score_gemma":0.0005753976,"domain_scores_codex":[0.9998841,0.0000176344,0.00001022126,0.00002147345,0.00002967842,0.00003684076],"domain_scores_gemma":[0.9999403,0.000007606341,0.00001589159,0.000005508778,0.000006977615,0.00002375399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001434181,0.00001133066,0.0002428464,0.00002400594,0.000003055003,0.00008519518,0.00001349454,0.00001298569,0.9980457,0.0001059002,0.00004446121,0.001267603],"study_design_scores_gemma":[0.00003582977,0.000317168,0.01757058,0.00002098292,0.00001768237,0.001515143,0.00009917212,0.0006395673,0.9727643,0.0001449595,0.006867307,0.000007416631],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884444,0.005756385,0.001935386,0.0001427141,0.00004120786,0.00003270029,0.0002444275,0.00005925653,0.003343642],"genre_scores_gemma":[0.9907335,0.001621882,0.003323089,0.00007514343,0.00002140132,0.00004944734,0.0004587308,0.00001830136,0.003698538],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001307519,"threshold_uncertainty_score":0.004374087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1319159985554597,"score_gpt":0.3641496392700644,"score_spread":0.2322336407146047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}